Der Maus Monoklonal anti-FGFR1b Antikörper (Klon M17A3) (ABIN2961626) detektiert spezifisch FGFR1b in IP, IHC und WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
Klon
M17A3
Bindungsspezifität
Ectodomain, Pro23
Spezifität
Reacts with human Fibroblast Growth Factor Receptor 1 beta (FGFR1β). Epitope is undetermined but presumed to be near junction of the common FGFr1 NH2-terminus and NH2-terminus of Ig loop II.
Aufreinigung
Purified (protein G)
Immunogen
Recombinant human ectodomain of FGFr1beta expressed in E. coli beginning with pro23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.
Isotyp
IgG2b
Applikationshinweise
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only : WB(1 μg/mL)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS, pH 7.4.
Handhabung
Dilute in PBS or medium that is identical to that used in the assay system.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.