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FAP Produkte

(Fibroblast Activation Protein, alpha (FAP))

Kategorien

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq, Jul 2008].

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Ausgewählte FAP Kategorien

FAP Antikörper

High quality antibodies with extensive validation data.

FAP ELISA Kits

Reliable ELISA kits for a wide range of species.

FAP Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FAP Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (6)
Kat. Nr. ABIN7193479
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP
Validierungen
  • (4)
  • (5)
Kat. Nr. ABIN560844
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7434938
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FAP ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955802
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955800
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955801
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FAP Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274584
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274585
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274586
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FAP Produkten

Miller, Nagy, Knapp, Laengle, Ponweiser, Groeger, Starkl, Bergmann, Wagner, Haschemi: "Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments." in: Cell metabolism, Vol. 26, Issue 5, pp. 788-800.e6, (2017) (PubMed).

Wolczyk, Zaremba-Czogalla, Hryniewicz-Jankowska, Tabola, Grabowski, Sikorski, Augoff: "TNF-α promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts." in: Cellular oncology (Dordrecht), Vol. 39, Issue 4, pp. 353-63, (2017) (PubMed).

Zhang, Jiang, Ling, Cao, Zhao, Tuo, She, Shen, Jiang, Hu, Pang: "Enhanced Antitumor Activity of EGFP-EGF1-Conjugated Nanoparticles by a Multitargeting Strategy." in: ACS applied materials & interfaces, Vol. 8, Issue 14, pp. 8918-27, (2016) (PubMed).

Evrard, Lecce, Michelis, Nomura-Kitabayashi, Pandey, Purushothaman, dEscamard, Li, Hadri, Fujitani, Moreno, Benard, Rimmele, Cohain, Mecham, Randolph, Nabel, Hajjar, Fuster, Boehm, Kovacic: "Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability." in: Nature communications, Vol. 7, pp. 11853, (2016) (PubMed).

Zhai, Zhang, Wang, Lu, Liu, Yu, Weng, Ding, Zhu, Shi: "Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 147, (2016) (PubMed).

Yang, Lin, Shi, Li, Liu, Yin, Dang, Chu, Fan, He: "FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling." in: Cancer research, Vol. 76, Issue 14, pp. 4124-35, (2016) (PubMed).

Bohonowych, Hance, Nolan, Defee, Parsons, Isaacs: "Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment." in: The Prostate, Vol. 74, Issue 4, pp. 395-407, (2014) (PubMed).

Chung, Hsu, Chu, Lin, Jiaang, Chen, Chen: "Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation." in: PLoS ONE, Vol. 9, Issue 2, pp. e88772, (2014) (PubMed).

Herrera, Herrera, Alba-Castellón, Silva, García, Loubat-Casanovas, Alvarez-Cienfuegos, Miguel García, Rodriguez, Gil, Ma Jesús Citores, Ma Jesús Larriba, Ignacio Casal, de Herreros, Bonilla, Peña: "Protumorigenic effects of Snail-expression fibroblasts on colon cancer cells." in: International journal of cancer, Vol. 134, Issue 12, pp. 2984-90, (2014) (PubMed).

Herrera, Herrera, Domínguez, Silva, García, García, Gómez, Soldevilla, Muñoz, Provencio, Campos-Martin, García de Herreros, Casal, Bonilla, Peña: "Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients." in: Cancer science, Vol. 104, Issue 4, pp. 437-44, (2013) (PubMed).

Synonyme und alternative Namen zu FAP

fibroblast activation protein (Fap), fibroblast activation protein alpha L homeolog (fap.L), fibroblast activation protein alpha (FAP), fibroblast activation protein, alpha (Fap), fibroblast activation protein alpha (fap), prolyl endopeptidase FAP (LOC100547273), fibroblast activation protein alpha (Fap), dppiv, DPPIV, FAP, fap-A, fapa, FAPA, gene 13, seprase

Bezeichner auf Proteinebene für FAP

  • fibroblast activation protein alpha
  • integral membrane serine protease
  • seprase
  • fibroblast activation protein, alpha
  • fibroblast activation protein, alpha subunit
  • gene 13
  • 170 kDa melanoma membrane-bound gelatinase
  • seprase-like
  • prolyl endopeptidase FAP
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