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EXOSC4 Proteine

(Exosome Component 4 (EXOSC4))
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC4 binds to ARE-containing RNAs (By similarity).

4 Treffer :

EXOSC4 Spezies: Human Wirt: Wheat germ Recombinant ELISA, AA, AP, WB
Produktnummer ABIN1353240
 
EXOSC4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Produktnummer ABIN5853354
 
EXOSC4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Produktnummer ABIN2129146
 
EXOSC4 Spezies: Rind (Kuh) Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7590696
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Western Blotting (WB)
  • Reaktivität
    • Human
    • Cow
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 1-245
    • AA 2-245
  • Konjugat
    • His tag
    • GST tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Hersteller
    • antibodies-online
    • CUSABIO

Aliase für EXOSC4 Proteine

exosome component 4 (exosc4) Proteine
exosome component 4 (EXOSC4) Proteine
exosome component 4 (CC1G_03561) Proteine
exosome component 4 S homeolog (exosc4.S) Proteine
exosome component 4 (Exosc4) Proteine
1110039I09Rik Proteine
1500001N04Rik Proteine
EXOSC4 Proteine
hRrp41p Proteine
p12A Proteine
RRP41 Proteine
Rrp41 Proteine
RRP41A Proteine
Rrp41p Proteine
SKI6 Proteine
Ski6p Proteine
zgc:73175 Proteine
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