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Human Monoclonal TDGF1 Primary Antibody für FACS - ABIN4897519
Watanabe, Bianco, Strizzi, Hamada, Mancino, Bailly, Mo, Wen, Miatkowski, Gonzales, Sanicola, Seno, Salomon: Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration. in The Journal of biological chemistry 2007
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Human Polyclonal TDGF1 Primary Antibody für ELISA, IHC - ABIN4300489
Lee, Jung, Cho, Kim, Lee, Kim, Lee, Shim: GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer. in Cancer research and treatment : official journal of Korean Cancer Association 2015
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Human Polyclonal TDGF1 Primary Antibody für ICC, FACS - ABIN151145
Sun, Shi, Li, Jiang, Fu, Guo: Lefty inhibits glioma growth by suppressing Nodal-activated Smad and ERK1/2 pathways. in Journal of the neurological sciences 2014
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Human Monoclonal TDGF1 Primary Antibody für ELISA, WB - ABIN967164
van Dijk, van Den Akker, Amelsvoort, Mano, Löwenberg, von Lindern: Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells. in Blood 2000
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Results identified elevated CR-1 (zeige CR1 Antikörper) expression in esophageal squamous cell carcinoma (ESCC) specimens which correlated to poor prognosis of the patients. CR-1 (zeige CR1 Antikörper) high cells isolated from ESCC cells possess cancer stem-like cells (ECSLC) properties.
These results highlight a functional role for CRIPTO and GRP78 (zeige HSPA5 Antikörper) in prostate cancer metastasis and suggest that targeting CRIPTO/GRP78 (zeige HSPA5 Antikörper) signaling may have significant therapeutic potential.
PGAP6 plays a critical role in Nodal signaling modulation through CRIPTO shedding.
Upregulation of cripto-1 (zeige CFC1 Antikörper) is associated with prostate cancer.
the miR (zeige MLXIP Antikörper)-15b expression is negatively associated with the cripto-1 (zeige CFC1 Antikörper) expression in glioma cells. miR (zeige MLXIP Antikörper)-15b may subsequently impair growth and invasion of glioma cells through targeted regulation of cripto-1 (zeige CFC1 Antikörper).
These findings suggest that CRIPTO expression may be a useful serological marker for diagnostic and/or prognostic purposes during germ cell cancer management.
serum CR-1 (zeige CR1 Antikörper) is a useful diagnostic and prognostic marker for nonsmall cell lung cancer patients.
Cripto-1 (zeige CFC1 Antikörper) overexpression contributes to aggressiveness and poor prognosis of hepatocellular carcinoma
The main signaling pathways mediating Cripto-1 (zeige CFC1 Antikörper) effects include Nodal-dependent (Smad2 (zeige SMAD2 Antikörper)/3) and Nodal-independent (Src (zeige SRC Antikörper)/p44 (zeige GTF2H2 Antikörper)/42/Akt (zeige AKT1 Antikörper)) signaling transduction pathways
Cripto-1 (zeige CFC1 Antikörper) is a novel and dynamically regulated effector of stem cell functions in colorectal cancer.
MEF2C (zeige MEF2C Antikörper) has a role in regulating outflow tract alignment and transcriptional control of Tdgf1
Dissection of the mechanism by which this occurs indicates that mCripto-1 activates receptor activator NF-kappaB (zeige NFKB1 Antikörper)/receptor activator NF-kappaB (zeige NFKB1 Antikörper) ligand, and NF-kappaB (zeige NFKB1 Antikörper) signaling pathways.
our findings strongly suggest that Cripto-1 (zeige CFC1 Antikörper) is a potential driver of mammary tumorigenesis
CR1 protein fragments bind tightly to PfRh4 and also function as soluble inhibitors to block PfRh4 binding to red blood cells and to inhibit the PfRh4-CR1 invasion pathway
Data show that Cripto haploinsufficiency may be associated with increased tumorigenesis, suggesting that the effect of Cripto on tumor development is more complex and may strongly depend on the cellular context.
Cripto is transiently expressed in early differentiating myocardial cells of the left ventricle, right ventricle and outflow tract between late head fold stages and E8.5.
Cripto plays a critical role during mouse gastrulation, especially in mesoderm and endoderm formation
Cripto, a regulator of early embryogenesis, is a novel regulator of muscle regeneration and satellite cell progression toward the myogenic lineage.
These data suggest that Cripto/GRP78 signaling is an important pathway that regulates hematopoietic stem cell quiescence.
Reduced expression of Oep causes the loss of responsiveness to Nodal signals in the prospective ectoderm. Indeed, extending the presence of Oep prolongs the window of competence to respond to Nodal signals.
Late zygotic oep mutants have strongly reduced or absent pitx2 (zeige PITX2 Antikörper) expression in the lateral plate mesoderm (LPM), but this expression can be rescued to strong levels by restoring oep in midline structures only.
Nodal-BMP signaling cascade drives left-right heart morphogenesis by regulating the speed and direction of cardiomyocyte movement
Using mutants in the Nodal receptor cofactor one-eyed pinhead (oep) and the T-box transcription factors spadetail (spt (zeige AGXT Antikörper)) and no tail (ntl), we were able to define distinctive regulation underlying these sequential phases of PGP midline migration
heterozygote mutations in fgf8 (zeige FGF8 Antikörper), shh (zeige SHH Antikörper) or oep lead to a reduced number of ascending dopaminergic neurons in zebrafish and may confer increased susceptibility to the Parkinson disease
Vg1 and GDF1 (zeige GDF1 Antikörper) signaling require one-eyed pinhead.
Interplay between FGF, one-eyed pinhead (zoep), and T-box transcription factors spt (zeige AGXT Antikörper) and ntl during zebrafish posterior
Spatial and temporal regulation of FRL1 protein expression during the gastrula stage are demonstrated.
findings show that vegetal cell-specific translational repression of xCR1 mRNA contributes to the spatially restricted accumulation of the xCR1 protein in Xenopus embryos
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.
cripto-1 growth factor
, epidermal growth factor-like cripto protein CR1
, TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)
, cripto growth factor
, epidermal growth factor-like Cripto protein
, teratocarcinoma-derived growth factor
, cryptic protein
, one eyed pinhead
, teratocarcinoma-derived growth factor 1
, fibroblast growth factor receptor ligand 1
, teratocarcinoma-derived growth factor 3