This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Alternative names and synonyms associated with GPER
G protein-coupled estrogen receptor 1 (GPER1) ELISA Kit
G protein-coupled estrogen receptor 1 (GPER) ELISA Kit
G protein-coupled estrogen receptor 1 (Gper1) ELISA Kit