EGFR Proteine
(Epidermal Growth Factor Receptor (EGFR))
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
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EGFR
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
EGFR
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
EGFR
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
EGFR
Spezies: Maus
Wirt: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, ELISA, Imm, AcA
Active
EGFR
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
EGFR
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
EGFR
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
EGFR
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
EGFR
Spezies: Human
Wirt: Insect cells (Sf9)
Recombinant
>90 % (SDS-PAGE)
SDS
EGFR
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
90 %
ELISA
1 image
EGFR
Spezies: Human
Wirt: CHO Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
EGFR
Spezies: Human
Wirt: Baculovirus
Recombinant
WB, KAA
Active
1 image
EGFR
Spezies: Human
Wirt: Insect cells (Sf9)
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
EGFR
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
EGFR
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
EGFR
Spezies: Human
Wirt: CHO Cells
Recombinant
<= 95 % by SDS-PAGE gel and HPLC analyses.
Active
Aktuelle Publikationen für unsere EGFR Proteine
: "A Cell-free Expression Pipeline for the Generation and Functional Characterization of Nanobodies." in: Frontiers in bioengineering and biotechnology, Vol. 10, pp. 896763, (2022) (PubMed).: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." in: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).
: "Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery." in: Nature biotechnology, Vol. 36, Issue 8, pp. 707-716, (2019) (PubMed).
: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." in: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).
: "An EGFR-targeting antibody-drug conjugate LR004-VC-MMAE: potential in esophageal squamous cell carcinoma and other malignancies." in: Molecular oncology, Vol. 13, Issue 2, pp. 246-263, (2019) (PubMed).
: "CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity." in: Nature biotechnology, (2019) (PubMed).
: "Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics." in: Scientific reports, Vol. 7, Issue 1, pp. 12946, (2019) (PubMed).
: "Mabfilin and Fabfilin - New antibody-scaffold fusion formats for multispecific targeting concepts." in: Protein expression and purification, Vol. 149, pp. 51-65, (2018) (PubMed).
: "AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor." in: The Journal of allergy and clinical immunology, Vol. 142, Issue 3, pp. 973-976.e11, (2018) (PubMed).
: "Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains." in: Scientific reports, Vol. 6, pp. 28643, (2018) (PubMed).
Aliase für EGFR Proteine
epidermal growth factor receptor (EGFR) ProteineEpidermal growth factor receptor (Egfr) Proteine
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra) Proteine
epidermal growth factor receptor (egfr1) Proteine
epidermal growth factor receptor (LOC5564544) Proteine
epidermal growth factor receptor (Egfr) Proteine
9030024J15Rik Proteine
AI552599 Proteine
C-erb Proteine
c-erbB Proteine
CG10079 Proteine
D-Egf Proteine
d-egf-r Proteine
D-EGFR Proteine
DEGFR Proteine
DEgfr Proteine
Degfr Proteine
dEGFR Proteine
dEgfr Proteine
dEGFR1 Proteine
DER Proteine
Der Proteine
der Proteine
DER/EGFR Proteine
DER/faint little ball Proteine
DER/top Proteine
DER/torpedo Proteine
DER1 Proteine
DER flb Proteine
Dmel\\CG10079 Proteine
DmHD-33 Proteine
EFG-R Proteine
Egf Proteine
EGF-R Proteine
Egf-r Proteine
EGFR Proteine
EGFr Proteine
EGfr Proteine
EgfR Proteine
egfr Proteine
egfr1 Proteine
EGFR12 Proteine
EGFR15 Proteine
EK2-6 Proteine
El Proteine
Elp Proteine
Elp-1 Proteine
Elp-B1 Proteine
Elp-B1RB1 Proteine
ERBB Proteine
Erbb Proteine
ErbB-1 Proteine
ERBB1 Proteine
Erbb2 Proteine
Errb1 Proteine
Errp Proteine
flb Proteine
HD-33 Proteine
HER1 Proteine
l(2)05351 Proteine
l(2)09261 Proteine
l(2)57DEFa Proteine
l(2)57Ea Proteine
l(2)57EFa Proteine
mENA Proteine
mor1 Proteine
PIG61 Proteine
TOP Proteine
top Proteine
top/DER Proteine
top/flb Proteine
Torpedo/DER Proteine
Torpedo/Egfr Proteine
torpedo/Egfr Proteine
torpedo/egfr Proteine
wa-2 Proteine
wa2 Proteine
Wa5 Proteine
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- EFHD2 Proteine
- EFHD1 Proteine
- EFHC2 Proteine
- EFHC1 Proteine
- EFCAB6 Proteine
- EFCAB4B Proteine
- EFCAB4A Proteine
- EFCAB1 Proteine
- EEFSEC Proteine
- EEF2K Proteine
- EEF2 Proteine
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