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E-cadherin Proteine

(Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008].

42 Treffer

CDH1 Spezies: Rind (Kuh) Wirt: Escherichia coli (E. coli) Recombinant SDS, WB
Produktnummer ABIN6378121
 
CDH1 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1657564
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • ELISA
    • Positive Control (PC)
    • Immunoprecipitation (IP)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Mass Spectrometry (MS)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Chicken
    • Cow
    • Pig
    • Cynomolgus
    • Monkey
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Human Cells
    • Mammalian Cells
    • Insect Cells
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 155-707
    • AA 155-709
    • AA 157-709
    • AA 23-706
    • AA 1-713
    • AA 1-882
    • AA 153-264
    • AA 155-262
    • AA 155-266
    • AA 155-375
    • AA 155-708
    • AA 23-621
    • AA 23-647
    • AA 24-709
    • AA 24-713
    • AA 263-375
    • AA 373-621
    • AA 374-628
    • AA 375-631
    • AA 376-486
    • AA 487-593
    • AA 594-709
    • AA 751-884
    • AA 784-870
    • partial
  • Konjugat
    • His tag
    • Fc Tag
    • Unkonjugiert
    • GST tag
    • His tag,GST tag
    • His tag,SUMO Tag
    • Myc-DYKDDDDK Tag
    • mFc Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • MALS verified
  • Hersteller
    • antibodies-online
    • Abbexa
    • ACROBiosystems
    • CUSABIO
    • Cohesion Biosciences
    • FabGennix
    • ITSI-Biosciences
    • OriGene
    • Signalway

Aktuelle Publikationen für unsere E-cadherin Proteine

Eshghi, Gaultney, England, Brûlé, Miras, Sato, Coburn, Bellalou, Moriarty, Haouz, Picardeau: "An extracellular Leptospira interrogans leucine-rich repeat protein binds human E- and VE-cadherins." in: Cellular microbiology, Vol. 21, Issue 2, pp. e12949, (2019) (PubMed).

Campbell, Salvi, OBrien, Superfine, DeMali: "PAK2 links cell survival to mechanotransduction and metabolism." in: The Journal of cell biology, Vol. 218, Issue 6, pp. 1958-1971, (2019) (PubMed).

Suffoletto, Jetta, Hua: "E-cadherin mediated lateral interactions between neighbor cells necessary for collective migration." in: Journal of biomechanics, Vol. 71, pp. 159-166, (2019) (PubMed).

Aliase für E-cadherin Proteine

cadherin 1 (CDH1) Proteine
si:busm1-180o5.2 (si:busm1-180o5.2) Proteine
cadherin 1, type 1, E-cadherin (epithelial) (cdh1) Proteine
cadherin 1 (Cdh1) Proteine
cadherin 1, type 1 S homeolog (cdh1.S) Proteine
AA960649 Proteine
Arc-1 Proteine
arc-1 Proteine
c-cadherin Proteine
cadherin-1 Proteine
CD324 Proteine
cd324 Proteine
cdh1 Proteine
cdhc-A Proteine
CDHE Proteine
cdhe Proteine
E-Cad Proteine
E-cad Proteine
E-cadherin Proteine
ECAD Proteine
ecad Proteine
Ecad Proteine
l-cam Proteine
L-CAM Proteine
LCAM Proteine
lcam Proteine
si:dz180o5.2 Proteine
Um Proteine
UVO Proteine
uvo Proteine
uvomorulin Proteine
xb-cad Proteine
XB-cadherin Proteine
XBcad Proteine
xcdh1 Proteine
XTCAD-1 Proteine
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