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DNASE1 Proteine

(Deoxyribonuclease I (DNASE1))
This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].

Häufig verwendete DNASE1 Proteine

Aliase für DNASE1 Proteine

DNase I (endA) Proteine
DNase I (LOC397802) Proteine
deoxyribonuclease 1 (DNASE1) Proteine
deoxyribonuclease I (Dnase1) Proteine
deoxyribonuclease 1 (Dnase1) Proteine
deoxyribonuclease I L homeolog (dnase1.L) Proteine
deoxyribonuclease I (dnase1) Proteine
deoxyribonuclease I (CpipJ_CPIJ011184) Proteine
deoxyribonuclease I (CpipJ_CPIJ011185) Proteine
deoxyribonuclease I (CpipJ_CPIJ011186) Proteine
deoxyribonuclease I (CpipJ_CPIJ011187) Proteine
deoxyribonuclease I (CpipJ_CPIJ011190) Proteine
deoxyribonuclease I (CpipJ_CPIJ017803) Proteine
Deoxyribonuclease I (Desal_1409) Proteine
deoxyribonuclease I (MPET_RS05255) Proteine
deoxyribonuclease I (METEV_RS02275) Proteine
deoxyribonuclease I (Plabr_0631) Proteine
AI788650 Proteine
dnase1-A Proteine
DNaseI Proteine
DNL1 Proteine
Dnl1 Proteine
DRNI Proteine
LOC397802 Proteine
zgc:92440 Proteine
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