DMPK Produkte
(Dystrophia Myotonica-Protein Kinase (DMPK))
Kategorien
The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte DMPK Kategorien
DMPK Antikörper
High quality antibodies with extensive validation data.
DMPK ELISA Kits
Reliable ELISA kits for a wide range of species.
DMPK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DMPK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN7073790
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (5)
Kat. Nr.
ABIN950119
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, RNAi
Validierungen
- (4)
Kat. Nr.
ABIN515032
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene DMPK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5648192
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1143793
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DMPK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5569694
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351723
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3114460
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DMPK Produkten
: "Impact of initial biofilm growth on the anode impedance of microbial fuel cells." in: Biotechnology and bioengineering, Vol. 101, Issue 1, pp. 101-8, (2008) (PubMed).: "Myotonic dystrophy protein kinase (DMPK) induces actin cytoskeletal reorganization and apoptotic-like blebbing in lens cells." in: Cell motility and the cytoskeleton, Vol. 45, Issue 2, pp. 133-48, (2000) (PubMed).
: "Localization of myotonic dystrophy protein kinase in human and rabbit tissues using a new panel of monoclonal antibodies." in: Human molecular genetics, Vol. 7, Issue 12, pp. 1957-65, (1998) (PubMed).
: "Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene." in: Human molecular genetics, Vol. 2, Issue 3, pp. 299-304, (1993) (PubMed).
Synonyme und alternative Namen zu DMPK
DM1 protein kinase (DMPK), dystrophia myotonica-protein kinase (Dmpk), DM1 protein kinase (Dmpk), DM, DM1, DM1PK, Dm15, DMK, DMPK, MDPK, MT-PKBezeichner auf Proteinebene für DMPK
- dystrophia myotonica-protein kinase
- myotonic dystrophy protein kinase
- myotonin-protein kinase-like
- DM protein kinase
- DM-kinase
- DM1 protein kinase
- myotonic dystrophy associated protein kinase
- myotonin protein kinase A
- myotonin-protein kinase
- thymopoietin homolog
- dystrophia myotonica kinase, B15
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