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Protective effect of JWA against paraquat neurotoxicity involves regulation of the MEK (zeige MDK ELISA Kits)/PI3K-Nrf2 (zeige NFE2L2 ELISA Kits) axis.
the JWA deficiency through cascading FAK (zeige PTK2 ELISA Kits)-PI3K-Akt (zeige AKT1 ELISA Kits)-mTOR (zeige FRAP1 ELISA Kits) pathway increases the newborn neurons.
These findings indicated that Arl6ip5 was an anti-catabolic factor by binding with RANKL (zeige TNFSF11 ELISA Kits) and disturbing its subcellular trafficking in osteoblast.
Arl6ip5 is a novel regulator of bone formation in osteoblasts.
This study provided evidence that astrocytic JWA expression protects DA neurons from degeneration and plays an important role in neuroprotection via inhibition of ROS (zeige ROS1 ELISA Kits) and NF-kappaB (zeige NFKB1 ELISA Kits) activation.
The double-fluorescent immunohistochemical analysis revealed that addicsin and TR1 were coexpressed in neurons
Data show the importance of JWA (Arl6ip5) in skin homeostasis and in the process of skin tumor development.
This study demonistrated that GTRAP3-18(-/-) mice performed better in motor/spatial learning and memory tests. The suppression of GTRAP3-18 increases neuronal resistance to oxidative stress by increasing GSH content and also facilitates cognitive function
Arl6ip1 (zeige ARL6IP1 ELISA Kits) is a novel addicsin-associated partner that promotes EAAC1 (zeige SLC1A1 ELISA Kits)-mediated glutamate (zeige GRIN1 ELISA Kits) transport activity by decreasing the number of addicsin molecules available for interaction with EAAC1 (zeige SLC1A1 ELISA Kits).
98% identity with that of rat GTRAP3-18; upregulated in the amygdala by repeated administration of morphine
Protective effect of JWA against paraquat neurotoxicity involves regulation of the MEK (zeige MAP2K1 ELISA Kits)/PI3K (zeige PIK3CA ELISA Kits)-Nrf2 (zeige GABPA ELISA Kits) axis.
JWA and topoisomerase II (zeige TOP2 ELISA Kits) alpha regulate each other in tumor cells arrested in G2/M.
the JWA gene may regulate human breast cancer cells through the MAPK (zeige MAPK1 ELISA Kits) signaling pathway using different types of regulation.
This review gives an overview of EAAC1 (zeige SLC1A1 ELISA Kits)-mediated GSH synthesis, and its regulatory mechanisms by GTRAP3-18 in the brain, and a potential approach against neurodegeneration.
JWA reverses cisplatin resistance via the CK2 (zeige CSNK2A1 ELISA Kits)-XRCC1 (zeige XRCC1 ELISA Kits) pathway in human gastric cancer cells.
data demonstrate that JWA plays a crucial role in HCC (zeige FAM126A ELISA Kits) progression and suggest JWA may be a potential prognostic biomarker and therapeutic target for HCC (zeige FAM126A ELISA Kits).
A significant negative correlation between JWA and ILK (zeige ILK ELISA Kits) in melanoma biopsies.
Loss of JWA expression was strongly correlated with increased gastric cancer angiogenesis.
JWA has an important role in ING4 (zeige ING4 ELISA Kits)-regulated melanoma angiogenesis, and ING4 (zeige ING4 ELISA Kits)/JWA/ILK (zeige ILK ELISA Kits) are promising prognostic markers and may be used as anti-angiogenic therapeutic targets for melanoma.
A combined effect of p53 (zeige TP53 ELISA Kits) with JWA as efficient prognostic indicators was found for the first time.
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
ADP-ribosylation-like factor 6 interacting protein 5
, ADP-ribosylation factor-like 6 interacting protein 5
, ADP-ribosylation factor-like protein 6-interacting protein 5
, ARL-6-interacting protein 5
, PRA1 family protein 3
, glutamate transporter EAAC1-interacting protein
, prenylated Rab acceptor protein 2
, protein JWa
, PRA1 domain family 3
, cytoskeleton related vitamin A responsive protein
, cytoskeleton-related vitamin A-responsive protein
, dermal papilla derived protein 11
, dermal papilla-derived protein 11
, glutamate transporter EEAC1-associated protein
, putative MAPK activating protein PM27
, putative MAPK-activating protein PM27
, glutamate transporter EAAC1 interacting protein
, PRA1 family protein-like protein