Daf-2 Antikörper (C-Term)
Dieses Anti-Daf-2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Daf-2 in IHC. Geeignet für C. elegans.
Produktnummer ABIN965970
Kurzübersicht für Daf-2 Antikörper (C-Term) (ABIN965970)
Target
Alle Daf-2 (DAF2) Produkte
Daf-2 (DAF2)
(Decay Accelerating Factor 2 (DAF2))
Reaktivität
C. elegans
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
Immunohistochemistry (IHC)
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Bindungsspezifität
- C-Term
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Aufreinigung
- Purified by antigen-specific affinity chromatography.
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Immunogen
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)
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Applikationshinweise
- ELISA, Western blotting: 1µg/ml for 2hrs.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- This antibody is stored in PBS, 50% glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
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Andere Bezeichnung
- Daf-2
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Hintergrund
- The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.
Target
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