DDB2 Proteine
(Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq, Jul 2008].
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DDB2
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
1 reference
DDB2
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
DDB2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
DDB2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
DDB2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
custom-made
DDB2
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
DDB2
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
DDB2
Spezies: Zebrafisch (Danio rerio)
Wirt: Hefe
Recombinant
> 90 %
ELISA
Aktuelle Publikationen für unsere DDB2 Proteine
: "Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1658-63, (2013) (PubMed).Aliase für DDB2 Proteine
damage specific DNA binding protein 2 (DDB2) Proteinedamage-specific DNA binding protein 2 (ddb2) Proteine
damage specific DNA binding protein 2 (Ddb2) Proteine
2610043A19Rik Proteine
DDBB Proteine
si:dkey-45f10.3 Proteine
UV-DDB2 Proteine
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