(Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008].
Marsters, Sheridan, Pitti, Huang, Skubatch, Baldwin, Yuan, Gurney, Goddard, Godowski, Ashkenazi: "A novel receptor for Apo2L/TRAIL contains a truncated death domain." in: Current biology : CB, Vol. 7, Issue 12, pp. 1003-6, (1998) (PubMed).
Pan, Ni, Yu, Wei, Dixit: "TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling." in: FEBS letters, Vol. 424, Issue 1-2, pp. 41-5, (1998) (PubMed).