CYP7A1 Produkte
(Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
Kategorien
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010].
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Ausgewählte CYP7A1 Kategorien
CYP7A1 Antikörper
High quality antibodies with extensive validation data.
CYP7A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP7A1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CYP7A1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p)
Validierungen
- (7)
- (2)
Kat. Nr.
ABIN739725
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (2)
Kat. Nr.
ABIN7433078
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN392530
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene CYP7A1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966253
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966254
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955264
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CYP7A1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7546829
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7557845
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN2565181
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CYP7A1 Produkten
: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." in: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).: "Parabacteroides distasonis Alleviates Obesity and Metabolic Dysfunctions via Production of Succinate and Secondary Bile Acids." in: Cell reports, Vol. 26, Issue 1, pp. 222-235.e5, (2020) (PubMed).
: "Nrf2 is crucial for the down-regulation of Cyp7a1 induced by arachidonic acid in Hepg2 cells." in: Environmental toxicology and pharmacology, Vol. 52, pp. 21-26, (2017) (PubMed).
: "Pyrazinamide Induced Rat Cholestatic Liver Injury through Inhibition of FXR Regulatory Effect on Bile Acid Synthesis and Transport." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 152, Issue 2, pp. 417-28, (2016) (PubMed).
: "Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters." in: Life sciences, Vol. 151, pp. 50-60, (2016) (PubMed).
: "Preferential gene expression and epigenetic memory of induced pluripotent stem cells derived from mouse pancreas." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 5, pp. 367-81, (2015) (PubMed).
: "In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism." in: Journal of ethnopharmacology, Vol. 153, Issue 3, pp. 763-70, (2014) (PubMed).
: "Chronic unpredictable mild stress combined with a high-fat diets aggravates atherosclerosis in rats." in: Lipids in health and disease, Vol. 13, pp. 77, (2014) (PubMed).
: "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 11, pp. 1373-81, (2014) (PubMed).
: "Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 44, Issue 12, pp. 1018-26, (2012) (PubMed).
Synonyme und alternative Namen zu CYP7A1
cytochrome P450 family 7 subfamily A member 1 (CYP7A1), cytochrome P450, family 7, subfamily a, polypeptide 1 (Cyp7a1), cytochrome P450, family 7, subfamily A, polypeptide 1 (CYP7A1), cytochrome P450 family 7 subfamily A member 1 (Cyp7a1), cholesterol 7-alpha-hydroxylase (Cyp7a1), cytochrome P450, family 7, subfamily A, polypeptide 1 (cyp7a1), CHAP, CP7A, CYP7, cyp7a1a, CYP7S1, CYPVII, zgc:63920Bezeichner auf Proteinebene für CYP7A1
- cholesterol 7-alpha-hydroxylase
- cholesterol 7-alpha-monooxygenase
- cytochrome P450 7A1
- cytochrome P450, subfamily VIIA polypeptide 1
- CYPVII
- cholesterol 7 alpha hydroxylase
- cytochrome P450, 7a1
- cholesterol 7 alpha-hydroxylase
- cholesterol 7alpha-hydroxylase
- cholesterol 7-alpha hydroxylase
- cytochrome P450 (cholesterol hydroxylase 7 alpha)
- Cholesterol 7-alpha-hydroxylase
- Cytochrome P450 7A1
- cytochrome P450, family 7, subfamily A, polypeptide 1a
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