(Cone Rod Dystrophy 1 (Autosomal Dominant) (CORD1))
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis under oxygen- and copper-deficient conditions. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
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Boldareva-Nuianzina, Bláhová, Sobotka, Koblízek: "Distribution and origin of oxygen-dependent and oxygen-independent forms of Mg-protoporphyrin monomethylester cyclase among phototrophic proteobacteria." in: Applied and environmental microbiology, Vol. 79, Issue 8, pp. 2596-604, (2013) (PubMed).
Hollingshead, Kopecná, Jackson, Canniffe, Davison, Dickman, Sobotka, Hunter: "Conserved chloroplast open-reading frame ycf54 is required for activity of the magnesium protoporphyrin monomethylester oxidative cyclase in Synechocystis PCC 6803." in: The Journal of biological chemistry, Vol. 287, Issue 33, pp. 27823-33, (2012) (PubMed).
Lang, Mueller, Hoernstein, Porankiewicz-Asplund, Vervliet-Scheebaum, Reski: "Simultaneous isolation of pure and intact chloroplasts and mitochondria from moss as the basis for sub-cellular proteomics." in: Plant cell reports, Vol. 30, Issue 2, pp. 205-15, (2011) (PubMed).
Synonyme und alternative Namen zu CRD1
cone rod dystrophy 1 (autosomal dominant) (CORD1), CORD, CRD1