CPSF4 Produkte
(Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
Kategorien
Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte CPSF4 Kategorien
CPSF4 Antikörper
High quality antibodies with extensive validation data.
CPSF4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CPSF4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7147920
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC (fro), IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN1386751
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC
Validierungen
- (2)
Kat. Nr.
ABIN6261007
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CPSF4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN1098798
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350238
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3125158
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CPSF4 Produkten
: "Alanine substitutions within a linker region of the influenza A virus non-structural protein 1 alter its subcellular localization and attenuate virus replication." in: The Journal of general virology, Vol. 92, Issue Pt 8, pp. 1832-42, (2011) (PubMed).Synonyme und alternative Namen zu CPSF4
cleavage and polyadenylation specific factor 4 (CPSF4), cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4), cleavage and polyadenylation specific factor 4 (LOC733099), cleavage and polyadenylation specific factor 4 (LOC100360200), cleavage and polyadenylation specific factor 4 S homeolog (cpsf4.S), cleavage and polyadenylation specific factor 4 (cpsf4), cleavage and polyadenylation specific factor 4 (Cpsf4), 30kDa, C79664, cpsf30, CPSF30, nar, NAR, neb1, NEB1Bezeichner auf Proteinebene für CPSF4
- no arches
- GLEAN_10339
- cleavage and polyadenylation specific factor 4
- cleavage and polyadenylation specificity factor subunit 4
- cleavage and polyadenylation specific factor 4, 30kDa
- CPSF 30 kDa subunit
- cleavage and polyadenylation specific factor 4, 30kD subunit
- cleavage and polyadenylation specificity factor 30 kDa subunit
- clipper homolog
- clipper/CPSF 30K
- musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit
- NS1 effector domain-binding protein 1
- cleavage-polyadenylation specificity factor, 30kD
- neb-1
- no arches homolog
- no arches-like zinc finger protein
- cleavage-polyadenylation specificity factor, 30 kD
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