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COPRS Proteine

(Coordinator of PRMT5, Differentiation Stimulator (COPRS))

Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression (By similarity).

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COPRS Protein (AA 1-184) (His tag)

custom-made COPRS Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant COPRS Protein, UniprotID Q9NQ92

3 Abbildungen

Produktnummer ABIN7546629

Details

COPRS Protein (AA 1-173) (His tag)

custom-made COPRS Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Coprs Protein, UniprotID Q9CQ13

3 Abbildungen

Produktnummer ABIN7560498

Details

COPRS Protein (His tag)

COPRS Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

Produktnummer ABIN7410052

Details

COPRS Protein (AA 1-173) (Strep Tag)

custom-made COPRS Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

Produktnummer ABIN3128232