CHM Produkte
(Choroideremia (Rab Escort Protein 1) (CHM))
Kategorien
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia\; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009].
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Ausgewählte CHM Kategorien
CHM Antikörper
High quality antibodies with extensive validation data.
CHM Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CHM Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Avian, Cat, Chicken, Cow, Dog, Donkey, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Applikation
WB
Validierungen
- (4)
Kat. Nr.
ABIN6254221
Menge
800 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7166973
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1881197
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene CHM Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3137373
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3094919
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Fish
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN5776968
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CHM Produkten
: "Progression of retinal pigment epithelial alterations during long-term follow-up in female carriers of choroideremia and report of a novel CHM mutation." in: Archives of ophthalmology, Vol. 127, Issue 7, pp. 907-12, (2009) (PubMed).: "Effect of a clinical pathway after laparoscopic surgery for colorectal cancer." in: Hepato-gastroenterology, Vol. 55, Issue 85, pp. 1315-9, (2008) (PubMed).
Synonyme und alternative Namen zu CHM
CHM, Rab escort protein 1 (CHM), choroideremia (Rab escort protein 1) (chm), choroideremia (Rab escort protein 1) L homeolog (chm.L), CHM, Rab escort protein 1 (Chm), choroidermia (RAB escort protein 1) (Chm), choroideremia (Rab escort protein 1) S homeolog (chm.S), CHM, chm, chm-a, chm-b, chml, DKFZp459K2154, DXS540, dxs540, GGTA, ggta, HSD-32, hsd-32, MGC68578, REP-1, rep-1, Rep-1, REP1, TCD, tcdBezeichner auf Proteinebene für CHM
- choroideremia (Rab escort protein 1)
- choroideremia
- Rab escort protein 1
- rab proteins geranylgeranyltransferase component A 2
- choroideremia protein
- rab proteins geranylgeranyltransferase component A 1
- REP-1
- choroideraemia protein homolog
- choroideremia protein homolog
- choroidermia
- rab escort protein 1
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