anti-Peripheral-Type Benzodiazepine Receptor (TSPO) Antikörper

Bezeichnung:: anti-Peripheral-Type Benzodiazepine Receptor Antikörper (TSPO)

Auf www.antikoerper-online.de finden Sie aktuell 72 Peripheral-Type Benzodiazepine Receptor (TSPO) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Peripheral-Type Benzodiazepine Receptor Kits (28) und Peripheral-Type Benzodiazepine Receptor Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 120 Peripheral-Type Benzodiazepine Receptor Produkte verfügbar.

Synonyme:: BPBS, Bzrp, DBI, IBP, LOC732875, LOC100136652, LOC100280949, MBR, mDRC, PBR, PBS, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, TSPO, Tspo1

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	TSPO	12257	P50637
	TSPO	24230	P16257
	TSPO	706	P30536
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Peripheral-Type Benzodiazepine Receptor Antikörper

Human Polyclonal TSPO Primary Antibody für ICC, IF - ABIN188570 : Fafalios, Akhavan, Parwani, Bies, McHugh, Pflug: Translocator protein blockade reduces prostate tumor growth. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)
Show all 7 Pubmed References
Human Polyclonal TSPO Primary Antibody für IHC, WB - ABIN222898 : Ji, Maeda, Sawada, Ono, Okauchi, Inaji, Zhang, Suzuki, Ando, Staufenbiel, Trojanowski, Lee, Higuchi, Suhara: Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 (PubMed)
Mouse (Murine) Polyclonal TSPO Primary Antibody für ELISA, WB - ABIN570960 : Morgan, Cheepala, Wang, Neale, Adachi, Nachagari, Leggas, Zhao, Boyd, Venkataramanan, Schuetz: Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice. in The Journal of biological chemistry 2012 (PubMed)
Human Polyclonal TSPO Primary Antibody für IHC, WB - ABIN4343997 : Foss, Liu, Mease, Wang, Pasricha, Pomper: Imaging Macrophage Accumulation in a Murine Model of Chronic Pancreatitis with (125)I-Iodo-DPA-713 SPECT/CT. in Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017 (PubMed)
Mouse (Murine) Polyclonal TSPO Primary Antibody für ELISA, WB - ABIN4343998 : Weisinger, Kelly-Hershkovitz, Veenman, Spanier, Leschiner, Gavish: Peripheral benzodiazepine receptor antisense knockout increases tumorigenicity of MA-10 Leydig cells in vivo and in vitro. in Biochemistry 2004 (PubMed)

Weitere Antikörper gegen Peripheral-Type Benzodiazepine Receptor Interaktionspartner

Mouse (Murine) Peripheral-Type Benzodiazepine Receptor (TSPO) Interaktionspartner

TSPO is therefore proposed as a novel outer mitochondrial membrane-based pathway to control intracellular Ca(2 (zeige CA2 Antikörper)+) dynamics and redox transients in neuronal cytotoxicity.
Critical role of TSPO in steroid biosynthesis and it may function at least in part via its regulation of DeltaPsim and effects on STAR.
Results showed that TSPO and other mitophagy related proteins, such as VDAC1 (zeige VDAC1 Antikörper), Pink1 (zeige PINK1 Antikörper) and Beclin1 (zeige BECN1 Antikörper) were significantly decreased by LH challenge. Moreover, KIFC2 (zeige KIFC2 Antikörper), relevant to the mitochondrial transport and Snap25 (zeige SNAP25 Antikörper), relevant to neurotransmitter vesicle release, were also obviously down-regulated in the LH mice, which further rendered supportive evidence for the existing mitochondrial dysfunction in LH mice.
A potential modulatory role of TSPO is in response to immune system deficit.
The expression of TSPO was found to be increased in the peri (zeige POSTN Antikörper)-hematomal brain region after intracerebral hemorrhage.
TSPO expression increases ( approximately 9-fold) in rodent-derived macrophages and microglia upon pro-inflammatory stimulation.
Data suggest that up-regulation of translocator protein 18kDa level during neuroinflammation may be an adaptive response mechanism, a way to provide more neurosteroids.
This study confirms TSPO deficiency does not affect viability and bronchial alveolar immune homeostasis.
These results suggested that Wuling powder exhibited an obvious antidepressant effect, which could be due to the improvement of TSPO-mediated mitophagy signaling pathway.
The loss of TSPO in the Central Nervous System did not result in overt developmental defects or phenotypes. The TSPO-/- mouse showed a decrease in glial fibrillary acidic protein (zeige GFAP Antikörper) expression, correlating with a decrease in astrogliosis in response to neural injury during Autoimmune Experimental Encephalomyelitis.

Human Peripheral-Type Benzodiazepine Receptor (TSPO) Interaktionspartner

Authors investigate the function of TSPO in cholesterol efflux from the RPE cells. We demonstrate in RPE cells that TSPO specific ligands promoted cholesterol efflux to acceptor (apo)lipoprotein and human serum, while loss of TSPO resulted in impaired cholesterol efflux.
suggest that both of the most important proapoptotic and anticancer proteins, p53 and TSPO
Study shows that fibromyalgia patients with the translocator protein high affinity binding genotype reported a higher pain intensity and more severe fibromyalgia symptoms compared to mixed/low affinity binders, and this was modulated by interaction with the serotonin transporter (zeige SLC6A4 Antikörper) gene.
Genome-wide significant (GWS) associations in single-nucleotide polymorphism (SNP)-based tests (P < 5 x 10(-8)) were identified for SNPs in PFDN1/HBEGF, USP6NL/ECHDC3, and BZRAP1-AS1.
TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis.
Findings suggest lower glial density or an altered activation state with lower TSPO expression in the hippocampus of alcohol dependent patients.
demonstrate a consistent down-regulation of TSPO mRNA and protein in macrophages activated to a pro-inflammatory, or 'M1' phenotype
These findings have important implications for understanding the biology of TSPO in activated macrophages and microglia in humans.
TSPO may serve a range of functions that can be viewed as downstream regulatory effects of its primary, evolutionary conserved role in cell metabolism and energy production.
We report for the first time, to our knowledge, the kinetic properties of the novel third-generation TSPO PET ligand (18)F-GE180 in humans: 2TCM4k is the optimal method to quantify the brain uptake, 90 min is the optimal scan length, and the Logan approach could be used to generate parametric maps. Although these control subjects have shown relatively low VT, the methodology presented here forms the basis for quantificati

Pig (Porcine) Peripheral-Type Benzodiazepine Receptor (TSPO) Interaktionspartner

PBR mRNA was the more abundant detected form in pig tissues and in warm kidney that underwent ischemia suggesting functional implications of PBR during the renal repair process.
Changes in TSPO expression in kidney regenerating tissue could be important for renal protection and maintenance of kidney function.

Peripheral-Type Benzodiazepine Receptor (TSPO) Antigen-Profil

Beschreibung des Gens

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported\; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

Alternative names and synonyms associated with Peripheral-Type Benzodiazepine Receptor (TSPO)

peripheral-type benzodiazepine receptor (LOC732875) Antikörper
peripheral-type benzodiazepine receptor (MAV_3896) Antikörper
Peripheral-type benzodiazepine receptor (xccb100_2086) Antikörper
putative peripheral-type benzodiazepine receptor (Smp_102510) Antikörper
peripheral-type benzodiazepine receptor (Sros_1911) Antikörper
translocator protein (tspo) Antikörper
translocator protein homolog (LOC100280949) Antikörper
hypothetical protein (PGTG_16395) Antikörper
translocator protein (TSPO) Antikörper
translocator protein (Tspo) Antikörper

BPBS Antikörper
Bzrp Antikörper
DBI Antikörper
IBP Antikörper
LOC732875 Antikörper
LOC100136652 Antikörper
LOC100280949 Antikörper
MBR Antikörper
mDRC Antikörper
PBR Antikörper
PBS Antikörper
pk18 Antikörper
PKBS Antikörper
PTBR Antikörper
Ptbzr Antikörper
PTBZR02 Antikörper
RATPTBZR02 Antikörper
TSPO Antikörper
Tspo1 Antikörper

Bezeichner auf Proteinebene für TSPO

peripheral-type benzodiazepine receptor , Peripheral-type benzodiazepine receptor , translocator protein , PKBS , benzodiazepine receptor, peripheral , isoquinoline-binding protein , mitochondrial benzodiazepine receptor , Benzodiazepin receptor (peripheral) , PBR , benzodiazepine peripheral binding site , peripheral benzodiazepine receptor , IBP , benzodiazepine receptor (peripheral)

GENE ID	SPEZIES
732875	Bombyx mori
4529395	Mycobacterium avium 104
6322197	Xanthomonas campestris pv. campestris str. B100
8346408	Schistosoma mansoni
8665189	Streptosporangium roseum DSM 43021
100136652	Oncorhynchus mykiss
100280949	Zea mays
10528866	Puccinia graminis f. sp. tritici CRL 75-36-700-3
443123	Ovis aries
12257	Mus musculus
24230	Rattus norvegicus
706	Homo sapiens
396592	Sus scrofa
281033	Bos taurus
474475	Canis lupus familiaris
418226	Gallus gallus
100722263	Cavia porcellus
100338710	Oryctolagus cuniculus

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