anti-Interleukin 8 (IL8) Antikörper

Zebrafish Interleukin 8 (IL8) Interaktionspartner

1. gene expression and epistasis analysis indicated that CXCL8(IL-8) was a functional target of vitamin D3-mediated HSPC (zeige PSMA7 Antikörper) regulation. Together, these findings highlight the relevance of developmental 1,25(OH)D3 availability for definitive hematopoiesis and suggest potential therapeutic utility in HSPC (zeige PSMA7 Antikörper) expansion

2. Targeted expression of the human oncogene (zeige RAB1A Antikörper) KRASG12V in zebrafish gills induces inflammation and cxcl8-l1 expression.

3. Data show that both Cxcl8-l1 and Cxcl8-l2 are required for larva survival upon Salmonella Typhimurium infection.

4. results explain how early H2O2 signal regulates neutrophil recruitment at all phases, directly via Lyn (zeige LYN Antikörper) oxidation or indirectly by modulating cxcl8 gene expression

5. The data identify HOXC9 (zeige HOXC9 Antikörper) as an endothelial cell active transcriptional repressor promoting the resting, antiangiogenic endothelial cell phenotype in an interleukin 8-dependent manner

6. Here, we report the characterisation of genes encoding the zebrafish Cxcl8, Cxcr1 (zeige CXCR1 Antikörper) and Cxcr2 (zeige CXCR2 Antikörper)

Mouse (Murine) Interleukin 8 (IL8) Interaktionspartner

1. Topical application of glycolic acid suppresses the UVB induced IL-6 (zeige IL6 Antikörper), IL-8, MCP-1 (zeige CPT1B Antikörper) and COX-2 (zeige COX2 Antikörper) inflammation by modulating NF-kappaB (zeige NFKB1 Antikörper) signaling pathway in mouse skin.

2. Parenchymal polymorphonuclear myeloid-derived suppressor cell (PMN (zeige TBCE Antikörper)-MDSC), have a positive correlation with IL1a (zeige IL1A Antikörper), IL8, CXCL5 (zeige CXCL5 Antikörper), and Mip-1a (zeige CCL3 Antikörper), suggesting they may attract PMN (zeige TBCE Antikörper)-MDSC into the tumor

3. this study shows that ponciretin may attenuate ethanol-induced gastritis via the regulation of IL-8 secretion

4. Adh (zeige AVP Antikörper) binds to OR5M11 (zeige OR5M11 Antikörper), which enhances Actinobacillus pleuropneumoniae pathogenicity by activating p38 (zeige CRK Antikörper) which induces apoptosis of PAMs and IL-8 release

5. Findings suggest that IL8-dependent osteoclast activation may constitute an early event in the initiation of the joint specific inflammation in anti-citrullinated protein-positive rheumatoid arthritis.

6. Data suggest that CXCL1 (zeige CXCL1 Antikörper)/IL-8, released from osteoclasts in an autoantibody-dependent manner, produces pain by activating sensory neurons.

7. IL-8 signaling is up-regulated in alcoholic hepatitis.

8. expressions of IL-1beta (zeige IL1B Antikörper) and IL-8 in the brain increased after ApoE (zeige APOE Antikörper) knockout in mice

9. CYLD (zeige CYLD Antikörper) negatively regulates nontypeable Haemophilus influenzae-induced IL-8 expression via MKP-1 (zeige DUSP1 Antikörper)-dependent inhibition of ERK (zeige EPHB2 Antikörper).

10. Taken together, these results indicate that CD147 promotes lung cancer-induced osteoclastogenesis by modulating IL-8 secretion, and suggest that CD147 is a potential therapeutic target for cancer-associated bone resorption in lung cancer patients.

Human Interleukin 8 (IL8) Interaktionspartner

1. We discovered that IL-8 secreted from decidual stromal cells is a key cytokine enhancing the invasiveness of trophoblasts

2. these findings demonstrated that poly I:C accelerated collective HaCaT cell migration via autocrine/paracrine secretions of IL-8 and the subsequent incomplete epithelial-mesenchymal transition

3. GDNF has a role in lower than expected motor development, but while IL-1beta (zeige IL1B Antikörper) and CXCL8/IL-8 values were higher in the group with typical motor development among preterm neonates

4. Blocking of GPR68 (zeige GPR68 Antikörper) or NF-small ka, CyrillicB activity severely attenuated acidification induced IL-8 production.

5. Suggest that an increased concentration of IL-8 is associated with resting pain in rotator cuff (zeige CUFF Antikörper) tear patients.

6. The results of the transwell chemotaxis assay also supported the above results. Our data suggest that APN (zeige ANPEP Antikörper) can promote h-JBMMSC chemotaxis by up-regulating CXCL1 (zeige CXCL1 Antikörper) and CXCL8

7. Study concludes non-toxic concentrations of cadmium can stimulate interleukin-6 (IL-6 (zeige IL6 Antikörper)) and interleukin-8 (IL-8) release through MAPK (zeige MAPK1 Antikörper) phosphorylation and NF-kappaB (zeige NFKB1 Antikörper) activation. Suppressing IL-6 (zeige IL6 Antikörper) and IL-8 production could be novel approaches to prevent cadmium-induced angiogenesis in gliomas and inflammation in the brain.

8. IL-8 has an important role in HNSCC progression via CXCR1 (zeige CXCR1 Antikörper)/2-mediated NOD1 (zeige NOD1 Antikörper)/RIP2 (zeige ARHGEF28 Antikörper) signaling

9. Inter-group comparisons of cytokine levels demonstrated no significant differences in TNF-alpha (zeige TNF Antikörper), IL-6 (zeige IL6 Antikörper) and IL-8 cytokines levels. IL-10 (zeige IL10 Antikörper) level showed a moderately significant increase in the modified St. Thomas' group compared to the del Nido group after surgery (2.94+/-0.9 vs. 2.46+/-0.61 log10 pg/mL, respectively; p=0.039).

10. We suggest that a combination of H. pylori infection and the IL-8 -251 T > A polymorphism might increase the risk of severe AG and GC in a Korean population

Cow (Bovine) Interleukin 8 (IL8) Interaktionspartner

1. Molecular characterization of the bovine IER3 (zeige IER3 Antikörper) gene: Down-regulation of IL-8 by blocking NF-kappaB (zeige NFKB1 Antikörper) activity mediated by IER3 (zeige IER3 Antikörper) overexpression in MDBK cells infected with bovine viral diarrhea virus-1.

2. STA3 (zeige ARHGEF3 Antikörper) facilitates TLR4 (zeige TLR4 Antikörper)-dependent IL-6 (zeige IL6 Antikörper) and IL-8 production via IL-6 (zeige IL6 Antikörper) receptor-positive feedback in endometrial cells.

3. As a pilot study, the present results revealed that identified SNPs in IL8 and TLR4 (zeige TLR4 Antikörper) genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 (zeige TLR4 Antikörper) gene may be a potential candidate for such disease.

4. Blood levels of cortisol, immunoglobulin G, and IL-8 in relationship to genetics and the incidence of bovine respiratory complex disease are reported.

5. Genetic variation at the IL8 locus explains a proportion of the inter-breed and inter-individual variation in immunity between neonatal calves which is likely to influence their resistance to infection.

6. In response to C. abortus infection, both ovine and bovine turbinate cells produce CXCL8 mRNA and protein late in the bacterial developmental cycle.

7. Studied association of IL8 -105G/A with mastitis somatic cell score in Chinese Holstein dairy cows. Results suggest genotype GG may be a useful genetic marker for mastitis resistance selection and breeding in Chinese Holstein dairy cows.

8. Data implicate a complex cascade of events during luteolysis, involving Il8 signaling, neutrophil recruitment, and immune cell action within the corpus luteum.

9. Cadmium exposure induced pulmonary inflammation and increased lung interleukin 8 secretion.

10. Exposure to follicular fluid transiently increased the transcript levels of IL8 and PTGS2 (zeige PTGS2 Antikörper), and decreased the expression of SOD2 (zeige SOD2 Antikörper), GPX3 (zeige GPX3 Antikörper), DAB2 (zeige DAB2 Antikörper), and NR3C1 (zeige NR3C1 Antikörper). TNF (zeige TNF Antikörper) and IL6 (zeige IL6 Antikörper) levels were also decreased while those of NAMPT (zeige NAMPT Antikörper) were unaffected.

Pig (Porcine) Interleukin 8 (IL8) Interaktionspartner

1. The JNK (zeige MAPK8 Antikörper)-activated AP-1 (zeige JUN Antikörper) subunit c-Jun (zeige JUN Antikörper) was critical for the up-regulation of IL-8 expression by PRRSV

2. These results suggest that porcine circovirus 2 induces IL-8 secretion via the TLR2/MyD88 (zeige MYD88 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signalling pathway.

3. Facilitated degradation of the RGS16 (zeige RGS16 Antikörper) by porcine circovirus type 2 ORF3 (zeige ASZ1 Antikörper) further enhances NFkappaB translocation into the nucleus through the ERK1/2 signalling pathway and increased IL-6 (zeige IL6 Antikörper) and IL-8 mRNA transcripts.

4. Suggest that the interplay between TGFbeta (zeige TGFB1 Antikörper)-2 and LPS (zeige IRF6 Antikörper) regulates the levels of IL-8 in the immature newborn intestine.

5. Data suggest that MSK1 (zeige RPS6KA5 Antikörper) and MSK2 are the major CREB (zeige CREB1 Antikörper) kinases in fibroblast-like synoviocytes from rheumatoid arthritis patients stimulated with lysophosphatidic acid and that phosphorylation of CREB1 (zeige CREB1 Antikörper) at Ser (zeige SIGLEC1 Antikörper)-133 plays a significant role in IL-8 production.

6. Study presents evidence demonstrating a single species of exotoxin ApxI, derived from A. pleuropneumoniae serotype 10, induces the expression and production of proinflammatory cytokines IL-1beta (zeige IL1B Antikörper), IL-8 and TNF-alpha (zeige TNF Antikörper) in porcine alveolar macrophages.

7. local expression of IL-1beta (zeige IL1B Antikörper) and IL-8 in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls

8. In swine, IL-8, TNF-ALPHA (zeige TNF Antikörper), INOS (zeige NOS2 Antikörper) AND MIP-1BETA (zeige CCL4 Antikörper) were increased during mechanical ventilation in a time-related fashion.

9. Classical swine fever virus NS2 protein promotes interleukin-8 expression.

10. Developmental changes in IL-8 isoforms may serve to minimize its inflammatory effects in the fetus and also provide a mechanism to restore its full activity after birth

Rabbit Interleukin 8 (IL8) Interaktionspartner

1. At the 2-wk time point, interleukin 8 gene expression was comparable in intervertebral discs injected with chondrocytes in controls, whereas its expression in IVDs injected with saline increased 50-fold

2. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1 (zeige CCL2 Antikörper)) and interleukin-8 (IL-8) decreased significantly in Dachengqi decoction treatment group.

3. The JNK (zeige MAPK8 Antikörper) pathway plays an important role in mechanical ventilation-stimulated TNF-alpha (zeige TNF Antikörper) expression in alveolar macrophages, but the injury-stimulated IL-8 expression may be regulated by other signaling pathways.

4. IL-8 and IL-1ra (zeige IL1RN Antikörper) showed correlation with the severity of colitis. These observations should significantly further understandings on the role of neutrophils and monocytes in the immunopathogenesis of ulcerative colitis

Horse (Equine) Interleukin 8 (IL8) Interaktionspartner

1. Results suggested that chemokine (zeige CCL1 Antikörper) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

2. Mapped six genes (EIF4G3 (zeige EIF4G3 Antikörper), HSP90 (zeige HSP90AB1 Antikörper), RBBP6 (zeige RBBP6 Antikörper), IL8, TERT (zeige TERT Antikörper), and TERC) on the chromosomes of Equus caballus, Equus asinus, Equus grevyi, and Equus burchelli by fluorescence in situ hybridization.

3. This study examined effects of in vitro exposure to solutions of hay (zeige GTF2H5 Antikörper) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

4. These results suggest that MMP-1 (zeige MMP1 Antikörper) and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.

Rhesus Monkey Interleukin 8 (IL8) Interaktionspartner

1. Stress decreased IL-8 gene expression in both CeA (zeige CEACAM3 Antikörper) lesioned and non-lesioned animals. But, CeA (zeige CEACAM3 Antikörper) lesions increased the tissue expression of IL-8 mRNA prior to and after stress exposure.

Duck Interleukin 8 (IL8) Interaktionspartner

1. Duck IL-8 is good immunostimulant to enhance the immune efficiency of avian influenza vaccine in ducks.