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anti-Human Fibronectin 1 Antikörper:
anti-Mouse (Murine) Fibronectin 1 Antikörper:
anti-Rat (Rattus) Fibronectin 1 Antikörper:
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Chicken Monoclonal Fibronectin 1 Primary Antibody für ICC, IHC (fro) - ABIN3043242
Zhang, Chen, Qi, Wang, Xiao, Zhu: Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion. in Journal of cardiovascular pharmacology 2010
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Human Monoclonal Fibronectin 1 Primary Antibody für FACS, ELISA - ABIN969520
Ryschich, Khamidjanov, Kerkadze, Büchler, Zöller, Schmidt: Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer. in Pancreas 2009
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Human Monoclonal Fibronectin 1 Primary Antibody für FACS, IHC - ABIN969149
Huang, Zhang, Kim, Ge, Annis, Mosher, Greenspan: Fibronectin binds and enhances the activity of bone morphogenetic protein 1. in The Journal of biological chemistry 2009
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Human Monoclonal Fibronectin 1 Primary Antibody für FACS - ABIN4898545
Purushothaman, Bandari, Liu, Mobley, Brown, Sanderson: Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions. in The Journal of biological chemistry 2016
Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.
Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage
Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.
Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.
reduction of fn1 function enables rescue of cardiac fusion in hand2 (zeige HAND2 Antikörper) mutants
Fibronectin regulates epithelial organization during myocardial migration in zebrafish.
B. burgdorferi does not primarily target insoluble matrix Fn deposited on endothelial surfaces but, instead, recruits and induces polymerization of soluble plasma Fn (pFn), an abundant protein in blood plasma that is normally soluble and nonadhesive.
miR1271 inhibited glioma cell growth by targeting FN1, and a low level of miR1271 in glioma tumor tissues was associated with lower survival rates in patients with glioma.
There is a significant association between a positive fetal fibronectin result and underlying inflammatory pathology of the placenta, even more so than the recognized relationship with short cervical length.
The article focuses on summarizing the many binding partners for fibronectin such as extracellular matrix proteins, growth factors, and synthetic binding partners with a particular interest in binding partners whose adhesiveness is impacted by the molecular conformation of the fibronectin fibers. (Review)
FN1 fibrils regulate TGFB1 (zeige TGFB1 Antikörper)-induced epithelial-mesenchymal transition.
Breast cancer cells alter the dynamics of stromal fibronectin-collagen interactions.
This study suggested that high a1-antitrypsin (AAT (zeige SERPINA1A Antikörper))expression might be a negative prognostic marker for lung adenocarcinoma. AAT (zeige SERPINA1A Antikörper) promoted lung adenocarcinoma metastasis, whose functional target may be fibronectin . Our findings provide new insight into the mechanisms of lung adenocarcinoma metastasis
Data show the expression of ED-B fibronectin was much higher in mesenchymal than prostate cancer cells even after the epithelial to mesenchymal transition. Epithelial to mesenchymal transition is a key step for tumor progression contributing to the metastatic spread. Therefore, circulating cancer cells could seed into the metastatic niche taking advantage from the ED-B fibronectin that secrete their own.
Thrombomodulin (TM (zeige THBD Antikörper)) promotes angiogenesis by enhancing cell adhesion, migration, and FAK (zeige PTK2 Antikörper) activation through interaction with fibronectin.
thyroid nodule stiffness is correlated with fibrosis and expression of Gal-3 (zeige LGALS3 Antikörper) and FN-1
Factor XIII (zeige UGDH Antikörper)-A and TG2 (zeige TGM2 Antikörper) regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow.
we disclosed the role of chemotaxis and apoptosis in the fibrotic microenvironment-enhanced seeding of tumor cells and identified the fibroblast-derived FN1 and SPP1 (zeige SPP1 Antikörper) as the central mediators in these processes
PD increased CKIP-1 and Nrf2 (zeige NFE2L2 Antikörper) levels in the kidney tissues as well as improved the anti-oxidative effect and renal dysfunction of diabetic mice, which eventually reversed the up-regulation of FN and ICAM-1 (zeige ICAM1 Antikörper)
Histone methyltransferase Suv39h1 (zeige SUV39H1 Antikörper) attenuates high glucose-induced fibronectin and p21(WAF1 (zeige CDKN1A Antikörper)) in mesangial cells
fibronectin has a critical role in tissue morphogenesis and the development of tissue heterogeneities
The aged stem cell niche in skeletal muscle contains reduced levels of FN, leading to detrimental consequences for the function and maintenance of muscle stem cells (MuSCs). FN is a preferred adhesion substrate for MuSCs and integrin-mediated signaling via focal adhesion kinase and the p38 MAPK (zeige MAPK14 Antikörper) pathway is strongly de-regulated in MuSCs from aged mice because of insufficient attachment to the niche.
analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation
scleraxis (zeige SCX Antikörper) was required for TGFbeta (zeige TGFB1 Antikörper)-induced fibronectin expression: TGFbeta (zeige TGFB1 Antikörper) lost its ability to induce fibronectin expression following scleraxis (zeige SCX Antikörper) knockdown.
The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 (zeige LGALS3 Antikörper) as opposed to fibronectin.
Thus, similarly to growth factor signaling, fibronectin matrix assembly during early development can be both autocrine and paracrine.
plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.
Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (zeige TGFB1 Antikörper) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.
Putative function of fibronectin and its receptor (integrin alpha(5 (zeige ITGA5 Antikörper))beta(1)) in male and female gametes during bovine fertilization in vitro.
These results highlight a crucial role for caveolin-1 (zeige CAV1 Antikörper) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.
P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn
The expression of extracellular matrix molecules fibronectin and osteopontin (zeige SPP1 Antikörper) in vitreous and retina samples in autoimmune uveitis was investigated.
The expression of the differentiation and stemness genes, FN1 and SOX9 (zeige SOX9 Antikörper), is accompanied by cell proliferation.
The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.
The relationship between hyaluronan synthesis and levels of versican (zeige Vcan Antikörper), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.
fibronectin has a cryptic binding site for tenascin (zeige TNC Antikörper)
Transplantation experiments demonstrate a tissue-autonomous role for DS epimerase (zeige DSE Antikörper)-1 in cranial neural crest (NC) cell migration in vivo Cranial NC explant and single-cell cultures indicate a requirement of DS epimerase (zeige DSE Antikörper)-1 in cell adhesion, spreading and extension of polarized cell processes on fibronectin.
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
, gene C
, cold-insoluble globulin
, migration-stimulating factor
, cumulus cell-specific fibronectin 1 transcript
, embryo-specific fibronectin 1 transcript
, fibronectin ED-A- region
, fibronectin variable region