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anti-Human ABCA1 Antikörper:
anti-Rat (Rattus) ABCA1 Antikörper:
anti-Mouse (Murine) ABCA1 Antikörper:
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Chicken Polyclonal ABCA1 Primary Antibody für ChIP, ELISA - ABIN152883
Krimbou, Denis, Haidar, Carrier, Marcil, Genest: Molecular interactions between apoE and ABCA1: impact on apoE lipidation. in Journal of lipid research 2004
Show all 259 Pubmed References
Chicken Polyclonal ABCA1 Primary Antibody für ELISA, ICC - ABIN268847
Burgess, Kiss, Zheng, Zachariah, Marcel: Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux. in The Journal of biological chemistry 2002
Show all 13 Pubmed References
Chicken Polyclonal ABCA1 Primary Antibody für ELISA, IHC (fro) - ABIN268848
Murthy, Born, Mathur, Field: LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells. in Journal of lipid research 2002
Show all 13 Pubmed References
Mouse (Murine) Monoclonal ABCA1 Primary Antibody für IHC (p), WB - ABIN268899
Zhou, Choi, Li, Xu, Herz: LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. in PLoS ONE 2009
Show all 7 Pubmed References
Human Polyclonal ABCA1 Primary Antibody für WB - ABIN3043773
Shang, Yu, Wang, Chen, Fang, Yang, Zhou, Nie, Zhou, Zhou: Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells. in Molecular medicine reports 2014
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Human Polyclonal ABCA1 Primary Antibody für WB - ABIN3044206
Chen: Effects of Chinese Herbal Compound "Xuemai Ning"on Rabbit Atherosclerosis Model and Expression of ABCA1. in International journal of biomedical science : IJBS 2013
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Human Monoclonal ABCA1 Primary Antibody für CyTOF, FACS - ABIN4277133
Wang, Zhang, Chou, Liang, Gu, Ma: Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. in American journal of physiology. Renal physiology 2009
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Chicken Polyclonal ABCA1 Primary Antibody für ELISA, FACS - ABIN446266
Ingram, Crowther, Little, Freeman, Harliwong, Veleva, Hassall, Remke, Taylor, Hallahan: ABC transporter activity linked to radiation resistance and molecular subtype in pediatric medulloblastoma. in Experimental hematology & oncology 2013
Human Polyclonal ABCA1 Primary Antibody für IF (p), IHC (p) - ABIN732188
Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. in Molecular medicine reports 2016
Mouse (Murine) Monoclonal ABCA1 Primary Antibody für FACS, IF - ABIN2477218
Zarubica, Trompier, Chimini: ABCA1, from pathology to membrane function. in Pflügers Archiv : European journal of physiology 2007
This study provides evidence that, in HepG2 cells, GLP-1 (zeige GCG Antikörper) may affect cholesterol homeostasis by regulating the expression of miR (zeige MLXIP Antikörper)-758 and ABCA1.
Hsp27 (zeige HSPB1 Antikörper) may up-regulate the expression of ABCA1 and promotes cholesterol efflux through activation of the PI3K (zeige PIK3CA Antikörper)/PKCzeta (zeige PRKCZ Antikörper)/Sp1 (zeige PSG1 Antikörper) signal pathway in THP-1 (zeige GLI2 Antikörper) macrophage-derived foam cells
the present study revealed that overexpression of GLP1R (zeige GLP1R Antikörper) significantly reduces proliferation, migration and cytokine release in ASM (zeige SMPD1 Antikörper) cells from COPD (zeige ARCN1 Antikörper) patients; this involved a significant increase in ABCA1 expression levels. This provided evidence to suggest that GLP1R (zeige GLP1R Antikörper) may be a potential therapeutic target for the treatment of COPD (zeige ARCN1 Antikörper).
Abnormal expression of ABCA1 may be associated with the dysregulation of placental lipid metabolism and the occurrence or development of spontaneous deliveries.
apoA-II (zeige APOA2 Antikörper) enhanced ABCA1-mediated cholesterol efflux
Cholesterol efflux from THP-1 (zeige GLI2 Antikörper) macrophages is decreased in the presence of plasma obtained from humans and rats with mild hyperbilirubinemia. A direct effect of unconjugated bilirubin on cholesterol efflux was demonstrated and is associated with decreased ABCA1 protein expression.
identified HuR (zeige ELAVL1 Antikörper) as a novel posttranscriptional regulator of ABCA1 expression and cellular cholesterol homeostasis, thereby opening new avenues for increasing cholesterol efflux from atherosclerotic foam macrophages and raising circulat-ing HDL (zeige HSD11B1 Antikörper) cholesterol levels.
Hepatic ABCA1 deficiency results in increased hepatic triglyceride and ANGPTL3 (zeige ANGPTL3 Antikörper) secretion, potentially underlying the elevated plasma triglyceride levels in Tangier disease patients.
ABCA1-derived nascent high-density lipoprotein-apolipoprotein AI (zeige APOA1 Antikörper) and lipids metabolically segregate.
Hepatic free cholesterol content was significantly increased in NASH (zeige SAMSN1 Antikörper) as compared to non-NASH (zeige SAMSN1 Antikörper) subjects, while ABCA1 and ABCG1 (zeige ABCG1 Antikörper) protein levels significantly decreased with NASH (zeige SAMSN1 Antikörper) and fibrosis progression. The relative expression of miR (zeige MLXIP Antikörper)-33a and miR (zeige MLXIP Antikörper)-144 correlated inversely with ABCA1 but not with ABCG1 (zeige ABCG1 Antikörper) protein levels. miR (zeige MLXIP Antikörper)-33a/144 and their target gene ABCA1 may contribute to the pathogenesis of NASH (zeige SAMSN1 Antikörper) in morbidly obese subjects.
our results highlight the importance of the LXR (zeige NR1H3 Antikörper)/ABCA1 system in brain pericytes and suggest a new role for these cells in brain cholesterol homeostasis.
The expression and distribution of the bovine ABCA1 transporter using quantitative PCR and the sequencing of the entire ABCA1 coding region, including the proximal promoter region, are reported.
Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (zeige SCARB1 Antikörper) or ABCG1 (zeige ABCG1 Antikörper) but not ABCA1.
ABCA1 promoter variants affect transcription activity and plasma HDL (zeige HSD11B1 Antikörper) level in pigs
ABCA1 was up-regulated in monocytes of hypercholesterolemic pigs via oxidized-LDL and prior to development coronary atherosclerosis.
Both region-specific and ubiquitous (ABCA1) phenotype changes were identified as early prelesional responses of the endothelium to hypercholesterolemia
CSL112 elevation of ABCA1-dependent efflux may target atherosclerotic plaque for cholesterol removal.
(1) ABCA1 maintains optimal hepatocyte PM FC, through intracellular FC trafficking, for efficient insulin (zeige INS Antikörper) signaling; and (2) hepatocyte ABCA1 deletion produces a form of selective insulin (zeige INS Antikörper) resistance so that lipogenesis is suppressed but glucose metabolism remains normal
demonstrates behavior deficits caused by Abca1 deletion in APP (zeige APP Antikörper)/PS1DeltaE9 mouse model at an early stage of amyloid pathology. The basal deficits of Abca1ko, manifested by diminished cognitive performance, prevent them from coping with additional stressors, which is in part due to the impairment of neurite morphology in the hippocampus.
Rutaecarpine was identified to be a candidate that protected ApoE (zeige APOE Antikörper)(-/-) mice from developing atherosclerosis through preferentially promoting activities of ABCA1 and SR-BI (zeige SCARB1 Antikörper) within RCT (zeige FOXE3 Antikörper).
Abca1 has a protective role in atherosclerosis, it exerts detrimental effects on cardiac function after myocardial infarction
Caveolin-1 (zeige CAV1 Antikörper) enhances internalization and degradation of ABCA1 by its association with ABCA1
an important role for hepatic ABCA1 in regulating secretory trafficking and modulating VLDL expansion during the TG accretion phase of hepatic lipoprotein particle assembly
These studies showed that following brain ischemia, reactive astrocytes become phagocytic and engulf debris via the ABCA1 pathway.
PCSK9 (zeige PCSK9 Antikörper) plays a direct role on Abca1-mediated cholesterol efflux through a downregulation of Abca1 gene and Abca1 protein expression. This extrahepatic effect may influence relevant steps in the pathogenesis of atherosclerosis, such as foam cell formation.
apoA-I (zeige APOA1 Antikörper)/ABCA1-mediated cholesterol efflux without STAT3 (zeige STAT3 Antikörper) activation can reduce proinflammatory cytokine expression in macrophages.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
ATP-binding cassette sub-family A member 1
, ATP-binding cassette transporter A1
, cholesterol efflux regulatory protein
, ATP-binding cassette, sub-family A (ABC1), member 1
, ATP-binding cassette, sub-family A member 1
, ATP-binding cassette transporter 1
, Cholesterol efflux regulatory protein
, ATP-binding cassette transporter
, ATP-binding cassette, sub-family A member 1-like
, ATP-binding cassette sub-family A member 1-like
, ATP-binding cassette 1