Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human Catalase Antikörper:
anti-Mouse (Murine) Catalase Antikörper:
anti-Rat (Rattus) Catalase Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Cow (Bovine) Polyclonal Catalase Primary Antibody für IHC, ELISA - ABIN96131
Shashoua, Adams, Volodina, Li: New synthetic peptides can enhance gene expression of key antioxidant defense enzymes in vitro and in vivo. in Brain research 2004
Show all 7 Pubmed References
Cow (Bovine) Polyclonal Catalase Primary Antibody für IHC, IHC (p) - ABIN4288222
Yang, Yang, Cao: Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells. in Molecular medicine reports 2015
Show all 4 Pubmed References
Pig (Porcine) Polyclonal Catalase Primary Antibody für IF (p), IHC (p) - ABIN679313
Wang, Zhao, Yu, Feng, Zhang, Kou, Chu, Cui, Li, Zhang, Shen, Min: Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis. in Toxicology and applied pharmacology 2016
Show all 3 Pubmed References
Human Polyclonal Catalase Primary Antibody für IHC, WB - ABIN6712140
Wang, Liu, Zhang, Zhang, Liao, Wang, Li, Qin, Hai: Oleanolic acid improves hepatic insulin resistance via antioxidant, hypolipidemic and anti-inflammatory effects. in Molecular and cellular endocrinology 2013
Show all 2 Pubmed References
Human Polyclonal Catalase Primary Antibody für ELISA, WB - ABIN285084
Makkar, Contreras, Paintlia, Smith, Haq, Singh: Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix. in Archives of biochemistry and biophysics 2006
Human Monoclonal Catalase Primary Antibody für IP, ELISA - ABIN532552
Putnam, Arvai, Bourne, Tainer: Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism. in Journal of molecular biology 2000
Dog (Canine) Polyclonal Catalase Primary Antibody für IHC (p), ELISA - ABIN547697
Schriner, Linford, Martin, Treuting, Ogburn, Emond, Coskun, Ladiges, Wolf, Van Remmen, Wallace, Rabinovitch: Extension of murine life span by overexpression of catalase targeted to mitochondria. in Science (New York, N.Y.) 2005
Low catalase expression confers redox hypersensitivity and identifies an indolent clinical behavior in CLL.
Both short interfering RNA-mediated silencing of catalase and pharmacological inhibition by 3-aminotriazole (3AT) decreased the number of peroxisomes and resulted in the downregulation of peroxisomal proteins, such as PMP70 and PEX14 under serum starvation.
the study showed that the CAT C-262T heterozygous genotype may be a genetic risk factor for developing abnormal liver function in Chinese epileptic patients treated with valproic acid monotherapy.
No significant association between CAT and GPx1 polymorphisms and coronary artery disease risk was observed.
Activation of catalase via co-administration of aspirin and pioglitazone: Experimental and MLSD simulation approaches.
With the only exception for CAT variant -89A/T, the other studied CAT gene polymorphisms (389C/T and 419C/T) might not be associated with vitiligo in Sicilian population
'T' allele of C262T showed a protective effect against the risk of ovarian cancer
There was no significant association between the CAT gene SNP rs1001179 and Type 1 Diabetes or Diabetic Peripheral Neuropathy.
Low CAT expression is associated with childhood obesity.
CAT rs769218 GG was associated with poor overall survival compared to GA/AA genotypes in patients without platinum and fluorouracil-based adjuvant chemotherapy.
homocysteine reacts with native catalase and/or redox-active transition metal ions to generate thiyl radicals that mediate compound II formation, a temporarily inactive state of the enzyme.
Data suggest catalase (CAT) rs769214 (-844 G > A) polymorphism may be associated with N,N-dimethylacetamide (DMAc)-induced abnormal liver function in Chinese population.
Maternal catalase activity was found to be lower in neural tube defect-affected pregnancies as compared to healthy controls.
Catalase SNPs (C-262T and A-21T) show positive correlation in the model of SNP-SNP interaction in systemic lupus erythematosus.
Study identifies an association of the polymorphism of CAT -262C/T in the Algerian population with type 1 diabetes without complications.
Findings suggest that gene-environment interactions between the catalase polymorphism rs769214 and mold odor may play an important role in childhood allergic rhinitis development.
catalase gene polymorphisms (rs1001179 and rs794316) have roles in cancer susceptibility [meta-analysis]
the association between the different Catalase -262C/T genotypes and Catalase levels in seminal plasma and and male infertility
This study showed that ADMA, carbonyl groups, CAT and NKA can be useful markers of chronic stress in both males and females with depression, PTSD, and depression concurrent with PTSD.
The investigated MnSOD and Catalase polymorphisms do not predispose to the development of alcoholic Chronic Pancreatitis.
It has been shown that genetic ablation of Nrf2 abolishes an adaptive muscle NQO1 activity and catalase induction.
Catalase overexpression modulates metabolic parameters in a new 'stress-less' leptin-deficient mouse model.
Catalase ameliorates diabetes-induced cardiomyopathy through reduced RelA-mediated transcription of BECN1.
Mitochondrial catalase induces neoplastic cell transformation through nucleolin-dependent Cox-2 mRNA stabilization.
Moderate MnSOD and/or catalase overexpression in desmin-null hearts leads to a marked decrease in intracellular reactive oxygen species, ameliorates mitochondrial and other ultrastructural defects, minimizes myocardial degeneration and leads to a significant improvement of cardiac function.
Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.
Mice devoid of catalase develop an obese, pre-diabetic phenotype and provide compelling evidence for catalase (or its products) being integral in metabolic regulation.
Data indicate that alpha-syntrophin plays an important role in the regulation of oxidative stress from endogenously generated reactive oxygen species (ROS) during myoblast differentiation by modulating the protein stability of catalase.
Overexpression of catalase reduced the concentrations of microsomal benzo(a)pyrene phenols and diols/diones by ~45 and 95%, respectively.
Results indicate that mitochondrial catalase likely functions to preclude the formation of high levels of H2O2 without perturbing redox-dependent signaling.
Age strongly interacts with catalase targeted to the mitochondria, consistent with antagonistic pleiotropy in the reverse of the typical direction.
data suggest that catalase is required not only to scavenge reactive oxygen species, but also to protect DNA from oxidative damage during meiotic maturation in mouse oocytes.
These results indicate that CAT expression is significantly decreased in the hippocampi of aged animals and decreased CAT expression may be closely associated with aging.
catalase protects mouse hearts against diabetic cardiomyopathy, partially by suppressing NF-kappaB-dependent inflammatory responses and associated protein nitration.
Hypoxia-generated red blood cells have low catalase and are preferentially destroyed.
The study shows how maturation of active catalase can be influenced by nitric oxide, S-nitrosylated GAPDH, and thioredoxin-1, and how maturation may become compromised in inflammatory conditions such as asthma.
Data suggest that embryonic catalase is a determinant of risk for EtOH embryopathies.
exposure to either 14- or 28-day chronic stress resulted in a depressive-like syndrome, behavioural invigoration and aggression, and decreased activity of two major brain peroxidation enzymes, superoxide dismutase and catalase.
The antioxidant catalase counteracts against high fat diet-induced cardiac geometric and functional anomalies possibly via an IKKbeta-AMPK-dependent restoration of myocardial autophagy.
fenofibrate almost completely abolished GM-induced reactive oxygen species generation, which seemed to be mediated at least in part by the restoration of the expression of PPARalphadependent antioxidant enzymes, including catalase and superoxide dismutase (SOD)-1.
Antioxidants diphenyliodonium and N-acetylcysteine or overexpression of zebrafish catalase in GF-1 cells also reduced ROS production and protected cells for enhancing host survival rate due to red-spotted grouper nervous necrosis virus infection.
Treatment of light responsive cells with hydrogen peroxide triggers induction of this gene.
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity.
Transcriptional activation of catalase by the DNA replication-related element (DRE)/DRE- binding factor (DREF) system.
The interactions between cationic surfactants dodecyltrimethylammonium bromide (DTAB) and tetradecyltrimethylammonium bromide (TTAB) with varying alkyl chain lengths and bovine liver catalase (BLC) were examined by various biophysical approaches.
Enzyme activity assay and molecular docking revealed that the activity of CAT was slightly inhibited in the presence of Sudan dyes. In comparison, the binding of Sudan II with CAT was slightly stronger than Sudan IV. Also, Sudan II and Sudan IV showed a different impact on the microenvironment of aromatic amino acid residues.
the decrease in accessible surface area and increase in pKa of important lysine residues were considered as predominant factors in decreased glycation of bovine liver catalase by curcumin.
ITC confirms the stability of bovine liver catalase (BLC)upon gemini combination. Docking provides support to fluorescence results by presenting the localization site of m-E2-m surfactants near to aromatic residues (mainly Tyr, Trp and Phe)
Data show that liver catalase is able to tolerate very high levels of the modifying alpha-oxoaldehyde methylglyoxal so that its essential enzymatic function is not impaired.
The structure of bovine liver catalase determined from a single crystal at 3.2 A resolution by MicroED, is reported.
These maps demonstrate that it is indeed possible to build atomic models from such crystals and even to determine the charged states of amino acid residues in the Ca(2+)-binding sites of Ca(2+)-ATPase and that of the iron atom in the heme in catalase.
Data indicate compatible osmolytes, proline, xylitol, and valine destabilize the denatured form of the catalase enzyme and, therefore, increase its disaggregation and thermal stability.
Flavonoid inhibition of catalase activity is, at least partially, due to the formation of hydrogen bonds between catalase and the flavonoid.
Comparison of deoxyferrous and oxyferrous complexes of cAOS and MAP with bovine liver catalase elucidates unresolved mechanistic questions in the catalytic cycles of these enzymes
Catalase is not influenced by the solvent during the catalytic reaction, which represents a lower energy barrier to be crossed in the overall energetics of the reaction, a fact that contributes to the high turnover rate of catalase.
At room temperature (25.0 degrees C) and higher, the addition of high concentrations of polymer is found to significantly enhance the affinity of SOD for catalase.
Immunohistochemistry in rectus abdominis muscle from foetuses at 180 and 260 days post-conception
study of bovine liver catalase and [14C]NADPH and [14C]NADH revealed that unbound NADPH or NADH are substrates for an internal reductase and transhydrogenase reaction respectively
Overexpression of catalase prevents the stimulation of reactive oxygen species and angiotensinogen mRNA in tubules owing to elevated glucose or angiotensin II in transgenic diabetic mice.
CAT transgenic mice became obese and hyperglycemic but had normal blood pressure and attenuated albuminuria compared with diabetic mice.
The structure of the active site of liver catalase B chain (PDB 4BLC) in the radical state (tyrosyl radical) was studied using EPR.
Data show that acriflavine induced in vitro a profound change in the structure of catalase so that the enzyme could no longer function.
Effect of beta-naphthoflavone on catalase in various brain regions of pig is reported.
The results obtained in this work suggest that variations of H(2)O(2) and catalase expression in Bombyx eggs are involved in diapause initiation and termination
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
, cytosolic catalase