anti-Desmoplakin (DSP) Antikörper

Bezeichnung:: anti-Desmoplakin Antikörper (DSP)

Auf www.antikoerper-online.de finden Sie aktuell 69 Desmoplakin (DSP) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Desmoplakin Kits (31) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 106 Desmoplakin Produkte verfügbar.

Synonyme:: 2300002E22Rik, 5730453H04Rik, AA407887, AA407888, AW109828, DP, dpi, dpii, DSP, im:6911953, sb:cb570, wu:fc17a08, wu:fk73d01

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	DSP	1832	P15924
	DSP	306871
	DSP	109620	E9Q557
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Desmoplakin (DSP) Antikörper

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anti-Human Desmoplakin Antikörper:

anti-Rat (Rattus) Desmoplakin Antikörper:

anti-Mouse (Murine) Desmoplakin Antikörper:

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Verknüpfte Pathways mit anti-Desmoplakin Antikörper

Cell-Cell Junction Organization

Weitere Produktkategorien zu Desmoplakin Antikörper

Am meisten referenzierte anti-Desmoplakin Antikörper

Human Polyclonal Desmoplakin Primary Antibody für ICC, IHC - ABIN1867641 : Kippenberger, Kleemann, Meissner, Steinhorst, Müller, Zouboulis, Kaufmann, Zöller: Activation of PKB/Akt and p44/42 by mechanical stretch utilizes desmosomal structures and the keratin filament. in Journal of dermatological science 2018 (PubMed)
Cow (Bovine) Polyclonal Desmoplakin Primary Antibody für ELISA - ABIN4267915 : Barahona-Dussault, Benito, Campuzano, Iglesias, Leung, Robb, Talajic, Brugada: Role of genetic testing in arrhythmogenic right ventricular cardiomyopathy/dysplasia. in Clinical genetics 2010 (PubMed)

Weitere Antikörper gegen Desmoplakin Interaktionspartner

Human Desmoplakin (DSP) Interaktionspartner

For arrhythmogenic right ventricular cardiomyopathy patients, both missense and non-missense desmoplakin mutations carry a high arrhythmic risk.
Here the authors identify a potential mechanism by which desmosomes assist the de-neddylating COP9 (zeige COPS8 Antikörper) signalosome (CSN) in attenuating EGFR (zeige EGFR Antikörper) through an association between the Cops3 (zeige COPS3 Antikörper) subunit of the CSN and desmosomal components, Desmoglein1 (Dsg1 (zeige DSG1 Antikörper)) and Desmoplakin (Dp), to promote epidermal differentiation.
Using molecular dynamics simulations, study elucidated the structural basis of post-translational modifications-induced effects. Simulations, nearing 2 mus (zeige TRPV6 Antikörper) in aggregate, indicate that phosphorylation of S2849 induces an "arginine claw" in desmoplakin's C-terminal tail.
Study identified DSP to be involved in the progressive intestinal injury associated with the development of Crohn's Disease complications via its effect on intestinal intercellular intermediate filament structure binding.
report for the first time in Korea on monozygotic twins with lethal acantholytic epidermolysis bullosa caused by two novel nonsense mutations in the DSP gene
Double heterozygotes for mutations in DSP and MYBPC3 (zeige MYBPC3 Antikörper) showed a variable clinical presentation of arrhythmogenic cardiomyopathy and hypertrophic cardiomyopathy.
Study reports a DSP mutation in an association with progressive cardiac conduction disease and a high risk of sudden death. The pathogenicity of the newly identified genetic variant was confirmed by in vitro prediction analysis and familial segregation. These results suggest that the effect of the mutation might be partially due to abnormal function of ion channels as a consequence of desmosomal remodeling.
DSP is a desmosomal protein critical to cell-cell adhesion in a variety of cell types and important in wound healing and epithelial barrier function.
Novel desmoplakin frameshift deletion p.Thr2625fs (c.7871_7872delAC) was identified as a potential cause of heart disease and sudden cardiac death in a Polish family.
This is the first report of DSP genetic screening in Chinese sudden unexplained nocturnal death syndrome (SUNDS) and Brugada syndrome. Our results imply that DSP mutations contribute to the genetic cause of some SUNDS victims and maybe a new susceptible gene for Brugada syndrome.

Mouse (Murine) Desmoplakin (DSP) Interaktionspartner

Deletion of Dsp under the transcriptional regulation of the CSPG4 (zeige MCSP Antikörper) locus led to phenotype resembling the human cardiocutaneous syndromes.
Conditional heterozygous deletion of Dsp in mice led to increased fibroadipogenesis in the heart and mild cardiac dysfunction.
Our data suggest that endurance exercise accelerates arrhythmogenic ventricular cardiomyopathy pathogenesis in transgenic DSP mice
GSK3- and PRMT-1 (zeige PRMT1 Antikörper)-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics.
These data indicate a function of desmoplakin in motor nerve regeneration by linking N-cadherin (zeige CDH2 Antikörper) to intermediate filaments in regenerating motor axons.
A loss of desmoplakin expression led to an abnormal distribution of Cx43 (zeige GJA1 Antikörper) and Nav1.5 (zeige SCN5A Antikörper), while scrapeloading dye/transfer revealed a decrease in dye transfer in DSP siRNAtreated cells.
the desmosomal protein desmoplakin is not essential for cell adhesion in the intestinal epithelium.
Fxr1 (zeige FXR1 Antikörper) knockout hearts exhibit an up-regulation of desmoplakin and talin2 proteins, which is accompanied by severe disruption of desmosome as well as costamere architecture and composition in the heart
Loss of desmoplakin expression and resultant disruption of desmosomal adhesion can promote increased local tumor invasion independent of adherens junction status.
desmoplakin has a role in capillary formation

Desmoplakin (DSP) Antigen-Profil

Beschreibung des Gens

Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.

Alternative names and synonyms associated with Desmoplakin (DSP)

desmoplakin (DSP) Antikörper
desmoplakin (PhopGV104) Antikörper
desmoplakin (ORF-59 desmoplakin) Antikörper
Desmoplakin (desmop) Antikörper
desmoplakin (Dsp) Antikörper
desmoplakin (dsp) Antikörper
ORF113 (desmoplakin) Antikörper
desmoplakin (desmoplakin) Antikörper
desmoplakin a (dspa) Antikörper
ORF112 DESMOPLAKIN (orf112 desmoplakin) Antikörper
orf102 (ClgVgp102) Antikörper
orf91; similar to Cydia pomonella granulovirus orf112 (COGV_gp091) Antikörper
ORF62 (APNV_p087) Antikörper
ORF-66 (CBNV_gp066) Antikörper
ORF57 (EONV_gp057) Antikörper
desmoplakin (OLNV_gp066) Antikörper
agip105 (AgipMNPV_gp105) Antikörper
desmoplakin (HaMNV_gp106) Antikörper
desmoplakin (EupsNPV_gp065) Antikörper
similar to XcORF133; similar to HaGV desmoplakin (PsunGV_gp139) Antikörper
desmoplakin L homeolog (dsp.L) Antikörper
ORF96 (ClanGV_gp096) Antikörper

2300002E22Rik Antikörper
5730453H04Rik Antikörper
AA407887 Antikörper
AA407888 Antikörper
AW109828 Antikörper
DP Antikörper
dpi Antikörper
dpii Antikörper
DSP Antikörper
im:6911953 Antikörper
sb:cb570 Antikörper
wu:fc17a08 Antikörper
wu:fk73d01 Antikörper

Bezeichner auf Proteinebene für anti-Desmoplakin (DSP) Antikörper

250/210 kDa paraneoplastic pemphigus antigen , desmoplakin I , desmoplakin II , desmoplakin , Desmoplakin , putative desmoplakin , desmoplakin I/II , desmosomal cytoskeletal connector molecule , fk73d01 , ORF112 DESMOPLAKIN , agip105 , desmoplakin-related protein

GENE ID	SPEZIES
1832	Homo sapiens
949289	Phthorimaea operculella granulovirus
3431549	Chrysodeixis chalcites nucleopolyhedrovirus
3890593	Hyphantria cunea nucleopolyhedrovirus
306871	Rattus norvegicus
100061514	Equus caballus
514360	Bos taurus
694860	Macaca mulatta
462420	Pan troglodytes
779453	Xenopus (Silurana) tropicalis
951777	Mamestra configurata nucleopolyhedrovirus B
1463319	Adoxophyes orana granulovirus
109620	Mus musculus
420869	Gallus gallus
324023	Danio rerio
921447	Cydia pomonella granulovirus
1725003	Cryptophlebia leucotreta granulovirus
4155920	Choristoneura occidentalis granulovirus
5141424	Antheraea pernyi nucleopolyhedrovirus
5141926	Clanis bilineata nucleopolyhedrovirus
5176508	Ectropis obliqua nucleopolyhedrovirus
5850536	Orgyia leucostigma NPV
6965873	Agrotis ipsilon multiple nucleopolyhedrovirus
7056761	Helicoverpa armigera multiple nucleopolyhedrovirus
7804620	Euproctis pseudoconspersa nucleopolyhedrovirus
8763999	Pseudaletia unipuncta granulovirus
398354	Xenopus laevis
488207	Canis lupus familiaris
10722977	Clostera anachoreta granulovirus
100027776	Monodelphis domestica
100083608	Ornithorhynchus anatinus
100354434	Oryctolagus cuniculus
100721053	Cavia porcellus
101119169	Ovis aries

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Show all anti-Desmoplakin (DSP) Antikörper with Pubmed References

Human Desmoplakin (DSP) Interaktionspartner

Mouse (Murine) Desmoplakin (DSP) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with Desmoplakin (DSP)

Bezeichner auf Proteinebene für anti-Desmoplakin (DSP) Antikörper