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Human Polyclonal CDH6 Primary Antibody für IHC (p), ELISA - ABIN542832
Shimoyama, Takeda, Yoshihara, Kitajima, Hirohashi: Biochemical characterization and functional analysis of two type II classic cadherins, cadherin-6 and -14, and comparison with E-cadherin. in The Journal of biological chemistry 1999
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Human Monoclonal CDH6 Primary Antibody für ICC, IHC (fro) - ABIN335402
Shimazui, Oosterwijk, Akaza, Bringuier, Ruijter, van Berkel, Wakka, van Bokhoven, Debruyne, Schalken: Expression of cadherin-6 as a novel diagnostic tool to predict prognosis of patients with E-cadherin-absent renal cell carcinoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 1998
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Human Polyclonal CDH6 Primary Antibody für ICC, IF - ABIN4286921
Sancisi, Gandolfi, Ragazzi, Nicoli, Tamagnini, Piana, Ciarrocchi: Cadherin 6 is a new RUNX2 target in TGF-β signalling pathway. in PLoS ONE 2013
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Human Polyclonal CDH6 Primary Antibody für IHC, IHC (p) - ABIN4286922
Wu, Hsu, Chen, Yu, Chang, Tai, Liu, Su, Chang, Yu: Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas. in Molecular & cellular proteomics : MCP 2010
Human Polyclonal CDH6 Primary Antibody für CyTOF, FACS - ABIN4899688
Dunne, Spring, Reheman, Jin, Berndt, Newman, Newman, Ni, Kenny: Cadherin 6 has a functional role in platelet aggregation and thrombus formation. in Arteriosclerosis, thrombosis, and vascular biology 2012
Human Polyclonal CDH6 Primary Antibody für WB - ABIN388173
Montserrat, Ramírez-Bajo, Xia, Sancho-Martinez, Moya-Rull, Miquel-Serra, Yang, Nivet, Cortina, González, Izpisua Belmonte, Campistol: Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, OCT4 and SOX2. in The Journal of biological chemistry 2012
Cadherin 6 expression in the nascent cortical plate may serve solidification of the protomap for cortical functional areas.
cadherin-6 plays essential roles in locomotor activity and ultrasonic vocalization
role of cadherin 6 as a novel ligand for alpha(IIb)beta(3) and highlights its function in thrombus formation.
Data show that during development, the adhesion molecule cadherin-6 is expressed by a subset of retinal ganglion cells and also by their targets in the brain.
Cadherin 6 is expressed in the floor and roof plates of the motor columns of the spinal cord.
identified a short 79-bp region that is implicated in regulating expression in cells once they have emigrated from the neural tube
Results describe the genetic control of Cdh6 expression by systematic integration of a reporter cassette into bacterial artificial chromosomes, with reporter activities evaluated in stable transgenic mouse lines.
These results suggest the role of Cdh6 in coordinating mouse hindbrain compartments possibly under the control of Hox gene regulatory network.
Tumor suppressor genes deleted in liver cancer 1 (DLC1), F-box/WD-repeat-containing protein 7 (FBXW7), and cadherin-6 (CDH6) were identified as presumed targets in Cholangiocarcinoma (CC).Inverse correlation between promoter methylation and expression suggested miR-129-2 and members of the miR-200 family (miR-200a, miR-200b, and miR-429) as novel tumor suppressors and oncomiRs, respectively, in CC
Data indicate that BRAFV600E, P-cadherin and cadherin 6 protein expressions were correlated with one another.
CDH6 is under the control of the transcription factor RUNX2, which we previously described as a crucial mediator of the Id1 pro-invasive function in thyroid tumor cells.
The chromatin modifications were determined at five PRC2 targets commonly underexpressed in multiple myeloma (CIITA, CXCL12, GATA2, CDH6 and ICSBP/IRF8). The selected genes were confirmed to be underexpressed in MM compared to normal plasma cells.
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
, kidney cadherin
, cadherin 6B