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CENPF Produkte

(Centromere Protein F (CENPF))

Kategorien

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008].

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Ausgewählte CENPF Kategorien

CENPF Antikörper

High quality antibodies with extensive validation data.

CENPF ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene CENPF Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p), IF, ICC, IHC (wm)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN2854654
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, WB, IP, IF
Validierungen
  • (5)
  • (4)
Kat. Nr. ABIN968167
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC (p), ICC, IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN7431644
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CENPF ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965627
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954556
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1745253
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CENPF Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1349108
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7390121
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CENPF Produkten

Yamauchi, Shibata, Suzuki, Suzuki, Niimi, Kondo, Miura, Hirakawa, Tsujita, Yamashita, Matsuda: "Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1." in: Scientific reports, Vol. 7, pp. 41812, (2018) (PubMed).

Chong, Sarac, Yao, Liao, Lyttle, Boutros, Bartlett, Spears: "Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer." in: Journal of ovarian research, Vol. 11, Issue 1, pp. 27, (2018) (PubMed).

Ciossani, Overlack, Petrovic, Huis In t Veld, Koerner, Wohlgemuth, Maffini, Musacchio: "The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases." in: The Journal of biological chemistry, Vol. 293, Issue 26, pp. 10084-10101, (2018) (PubMed).

Sikirzhytski, Renda, Tikhonenko, Magidson, McEwen, Khodjakov: "Microtubules assemble near most kinetochores during early prometaphase in human cells." in: The Journal of cell biology, Vol. 217, Issue 8, pp. 2647-2659, (2018) (PubMed).

Rodriguez-Rodriguez, Lewis, McKinley, Sikirzhytski, Corona, Maciejowski, Khodjakov, Cheeseman, Jallepalli: "Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion." in: Current biology : CB, Vol. 28, Issue 21, pp. 3422-3429.e5, (2018) (PubMed).

Magidson, He, Ault, OConnell, Yang, Tikhonenko, McEwen, Sui, Khodjakov: "Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells." in: The Journal of cell biology, Vol. 212, Issue 3, pp. 307-19, (2016) (PubMed).

Ma, Hou, Zhang, Sun, Schedl, Moley, Wang: "Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 9, pp. 4026-35, (2015) (PubMed).

Lee, Lee, Lee: "CaMKKβ-AMPKα2 signaling contributes to mitotic Golgi fragmentation and the G2/M transition in mammalian cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 4, pp. 598-611, (2015) (PubMed).

Nakajima, Hagiwara, Oike, Okayasu, Murakami, Nakano, Shibata: "Pre-exposure to ionizing radiation stimulates DNA double strand break end resection, promoting the use of homologous recombination repair." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122582, (2015) (PubMed).

Bee, Nasca, Zanolini, Cendron, dAdamo, Costa, Lamperti, Celotti, Ghezzi, Zeviani: "A nonsense mutation of human XRCC4 is associated with adult-onset progressive encephalocardiomyopathy." in: EMBO molecular medicine, Vol. 7, Issue 7, pp. 918-29, (2015) (PubMed).

Synonyme und alternative Namen zu CENPF

centromere protein F (CENPF), centromere protein F (Cenpf), centromere protein F (cenpf), 6530404A22Rik, AI325968, CENF, CMF1, hcp-1, im:7140452, im:7144238, im:7154719, im:7156761, Lek1, LOC100222985, mitosin, PRO1779, si:ch211-152h14.2

Bezeichner auf Proteinebene für CENPF

  • centromere protein F
  • centromere autoantigen F
  • leucine, glutamic acid, lysine family 1 protein
  • LEK/centromere protein
  • AH antigen
  • CENP-F kinetochore protein
  • cell-cycle-dependent 350K nuclear protein
  • centromere protein F, 350/400kDa (mitosin)
  • centromere protein F, 350/400ka (mitosin)
  • kinetochore protein CENPF
  • mitosin
  • cardiac muscle factor 1 CMF1
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