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CELF1 Produkte

(CUGBP, Elav-Like Family Member 1 (CELF1))

Kategorien

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte CELF1 Kategorien

CELF1 Antikörper

High quality antibodies with extensive validation data.

CELF1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CELF1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CELF1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP
Validierungen
  • (5)
Kat. Nr. ABIN6138399
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN948978
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN534074
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CELF1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Sheep
Analytical Method
Validierungen
Kat. Nr. ABIN1773938
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1743034
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1744255
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CELF1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1350750
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3091407
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3133586
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CELF1 Produkten

Liu, Ouyang, Rao, Zou, Xiao, Chung, Wu, Donahue, Gorospe, Wang: "Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal." in: Molecular biology of the cell, Vol. 26, Issue 10, pp. 1797-810, (2015) (PubMed).

Chung, Rao, Zou, Liu, Xiao, Gu, Turner, Yang, Wang: "Jnk2 deletion disrupts intestinal mucosal homeostasis and maturation by differentially modulating RNA-binding proteins HuR and CUGBP1." in: American journal of physiology. Cell physiology, Vol. 306, Issue 12, pp. C1167-75, (2014) (PubMed).

Yu, Rao, Zou, Liu, Xiao, Ouyang, Cao, Gorospe, Wang: "Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function." in: Molecular biology of the cell, Vol. 24, Issue 2, pp. 85-99, (2013) (PubMed).

de Haro, Al-Ramahi, Jones, Holth, Timchenko, Botas: "Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy." in: PLoS genetics, Vol. 9, Issue 4, pp. e1003445, (2013) (PubMed).

Xiao, Ford, Xu, Yan, Lee, Gonzales, West, Holtzman, Lee: "Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 39, pp. 13587-96, (2012) (PubMed).

Xiao, Cui, Rao, Zou, Liu, Smith, Turner, Gorospe, Wang: "Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines." in: Molecular biology of the cell, Vol. 22, Issue 17, pp. 3055-69, (2011) (PubMed).

Ward, Rimer, Killian, Dowling, Cooper: "CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1." in: Human molecular genetics, Vol. 19, Issue 18, pp. 3614-22, (2010) (PubMed).

Hashem, Galloway, Mori, Willemsen, Oostra, Paylor, Nelson: "Ectopic expression of CGG containing mRNA is neurotoxic in mammals." in: Human molecular genetics, Vol. 18, Issue 13, pp. 2443-51, (2009) (PubMed).

Orengo, Chambon, Metzger, Mosier, Snipes, Cooper: "Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2646-51, (2008) (PubMed).

Kress, Gautier-Courteille, Osborne, Babinet, Paillard: "Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice." in: Molecular and cellular biology, Vol. 27, Issue 3, pp. 1146-57, (2007) (PubMed).

Synonyme und alternative Namen zu CELF1

CUGBP Elav-like family member 1 (CELF1), CUGBP, Elav-like family member 1 (Celf1), cugbp, Elav-like family member 1 (celf1), CUGBP, Elav-like family member 1 (CELF1), CUGBP Elav-like family member 1 L homeolog (celf1.L), CUGBP Elav-like family member 1 (Celf1), 1600010O03Rik, AA407467, brul, Bruno-like, BRUNOL2, Brunol2, brunol2, cb920, CUG-BP, cug-bp, CUG-BP1, cug-bp1, CUGBP, cugbp, CUGBP1, Cugbp1, cugbp1, cugbp1-a, D2Wsu101e, EDEN-BP, eden-bp, edenbp, hNab50, HNAB50, NAB50, nab50, NAPOR

Bezeichner auf Proteinebene für CELF1

  • CUG triplet repeat, RNA binding protein 1
  • CUGBP Elav-like family member 1
  • 50 kDa nuclear polyadenylated RNA-binding protein
  • CELF-1
  • CUG RNA-binding protein
  • CUG triplet repeat RNA-binding protein 1
  • CUG triplet repeat, RNA-binding protein 1
  • CUG-BP- and ETR-3-like factor 1
  • CUG-BP1
  • EDEN-BP homolog
  • RNA-binding protein BRUNOL-2
  • bruno-like 2
  • bruno-like protein 2
  • deadenylation factor CUG-BP
  • embryo deadenylation element binding protein
  • embryo deadenylation element-binding protein homolog
  • nuclear polyadenylated RNA-binding protein, 50-kD
  • brain protein F41
  • deadenylation factor EDEN-BP
  • EDEN-BP/Bruno-like protein
  • CELF-1A
  • CUG triplet repeat RNA-binding protein 1-A
  • CUG-BP- and ETR-3-like factor 1-A
  • CUG-BP1-A
  • CUGBP Elav-like family member 1-A
  • EDEN-BP-A
  • RNA-binding protein BRUNOL-2-A
  • bruno-like protein 2-A
  • embryo deadenylation element-binding protein A
  • p53/p55
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