CDK2 Proteine
(Cyclin-Dependent Kinase 2 (CDK2))
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
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custom-made
CDK2
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
CDK2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CDK2
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
2 Referenzen
CDK2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
1 reference
CDK2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
CDK2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by reducing SDS-PAGE.
CDK2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
CDK2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
CDK2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 85 % as determined by reducing SDS-PAGE.
CDK2
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
custom-made
CDK2
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
CDK2
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Aktuelle Publikationen für unsere CDK2 Proteine
: "TarIKGC: A Target Identification Tool Using Semantics-Enhanced Knowledge Graph Completion with Application to CDK2 Inhibitor Discovery." in: Journal of medicinal chemistry, Vol. 68, Issue 2, pp. 1793-1809, (2025) (PubMed).: "A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization." in: Human mutation, Vol. 31, Issue 11, pp. E1825-35, (2010) (PubMed).
: "Peptide aptamers in label-free protein detection: 2. Chemical optimization and detection of distinct protein isoforms." in: Analytical chemistry, Vol. 81, Issue 9, pp. 3314-20, (2009) (PubMed).
: "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 5070-85, (2006) (PubMed).
Aliase für CDK2 Proteine
cyclin dependent kinase 2 (CDK2) Proteinecyclin-dependent kinase 2 (Cdk2) Proteine
cyclin dependent kinase 2 (Cdk2) Proteine
cyclin-dependent kinase 2 (cdk2) Proteine
cyclin-dependent kinase 2 S homeolog (cdk2.S) Proteine
cyclin-dependent kinase 2 (CDK2) Proteine
A630093N05Rik Proteine
cdk2L Proteine
CDKN2 Proteine
eg1 Proteine
p33(CDK2) Proteine
wu:fa10c02 Proteine
zgc:56598 Proteine
zgc:77684 Proteine
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- CDK5R1 Proteine
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- CDK5RAP3 Proteine
- CDK6 Proteine
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- CDK8 Proteine
- CDKAL1 Proteine
- CDKL1 Proteine
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- CDKL4 Proteine
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