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CDC6 Produkte

(Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Kategorien

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008].

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Ausgewählte CDC6 Kategorien

CDC6 Antikörper

High quality antibodies with extensive validation data.

CDC6 ELISA Kits

Reliable ELISA kits for a wide range of species.

CDC6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CDC6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, PLA
Validierungen
  • (5)
Kat. Nr. ABIN514244
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IP
Validierungen
  • (7)
Kat. Nr. ABIN2451939
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7147287
Menge 100 μg
Datenblatt Datenblatt

Empfohlene CDC6 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380160
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene CDC6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348865
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348864
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3091476
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CDC6 Produkten

Liu, Gong, Sun, Li: "FOXM1 and androgen receptor co-regulate CDC6 gene transcription and DNA replication in prostate cancer cells." in: Biochimica et biophysica acta, Vol. 1839, Issue 4, pp. 297-305, (2014) (PubMed).

Hubbi, Kshitiz, Gilkes, Rey, Wong, Luo, Kim, Dang, Levchenko, Semenza: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).

Alexandrow, Hamlin: "Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1614-27, (2004) (PubMed).

Clay-Farrace, Pelizon, Santamaria, Pines, Laskey: "Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1." in: The EMBO journal, Vol. 22, Issue 3, pp. 704-12, (2003) (PubMed).

Yim, Jin, Park, Choi, Lee: "Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis." in: Molecular biology of the cell, Vol. 14, Issue 10, pp. 4250-9, (2003) (PubMed).

Synonyme und alternative Namen zu CDC6

cell division cycle 6 (CDC6), cell division cycle 6 (Cdc6), CDC18L, HsCDC6, HsCDC18

Bezeichner auf Proteinebene für CDC6

  • CDC6 cell division cycle 6 homolog
  • CDC6-related protein
  • cdc18-related protein
  • cell division control protein 6 homolog
  • cell division cycle 6 homolog
  • p62(cdc6)
  • CDC18(S.pombe)
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