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CD47 Proteine

(CD47)
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].

66 Treffer

CD47 Spezies: Ratte Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Produktnummer ABIN5608234
 
CD47 Spezies: Kaninchen Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Produktnummer ABIN5608233
 
CD47 Spezies: Maus Wirt: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. WB, SDS, ELISA, MS
Produktnummer ABIN7314744
 
CD47 Spezies: Rhesusaffen, Cynomolgus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Produktnummer ABIN5608230
 
CD47 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Produktnummer ABIN5608232
 
MALS verified CD47 Spezies: Maus Wirt: HEK-293 Cells Recombinant 95 %
Produktnummer ABIN7482388
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Functional Studies (Func)
    • Activity Assay (AcA)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Standard (STD)
    • Mass Spectrometry (MS)
    • Affinity Purification (AP)
    • Positive Control (PC)
    • Antibody Array (AA)
    • Cell Culture (CC)
    • Phage Display (PhD)
    • Protein Interaction (PI)
    • Surface Plasmon Resonance (SPR)
    • Cryogenic electron microscopy (cryo-EM)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Rhesus Monkey
    • Cynomolgus
    • Rabbit
    • Dog
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Baculovirus infected Insect Cells
    • Mammalian Cells
    • Wheat germ
    • HEK-293T Cells
    • Insect cells (Sf9)
  • Bindungsspezifität
    • AA 19-139
    • AA 19-140
    • AA 19-141
    • partial
    • AA 19-158
    • AA 18-219
    • Transcript Variant 2
    • AA 1-323
    • AA 18-141
  • Konjugat
    • His tag
    • Fc Tag
    • Unkonjugiert
    • Fc Tag,AVI tag
    • His tag,AVI tag,Biotin
    • hIgG-His-tag
    • AVI tag,His tag
    • Biotin,Fc-Avi Tag
    • DYKDDDDK Tag
    • DYKDDDDK Tag,Strep Tag
    • DYKDDDDK-His Tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • Fc-Avi Tag,Biotin
    • GST tag
    • His tag,AVI tag
    • His tag,FITC
    • His-Avi Tag,Biotin
    • His-DYKDDDDK-Strep II Tag
    • mFc Tag
    • mFc-His Tag
  • Protein-Typ
    • Recombinant
    • Synthetic Nanodisc
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • MALS verified
  • Hersteller
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • OriGene
    • Cohesion Biosciences
    • Cloud-Clone

Aktuelle Publikationen für unsere CD47 Proteine

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Wang, Sun, Zhou, Chen, Jiao, Li, Gou, Li, Du, Chen, Zhai, Wu, Qi, Gao: "CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 8, Issue 2, (2020) (PubMed).

Yu, Qiu, Long, Yang, Zhang, Xu, Chang, Du, Hou, Yu, Zeng, Wang, Sun: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).

Weiskopf: "Cancer immunotherapy targeting the CD47/SIRPα axis." in: European journal of cancer (Oxford, England : 1990), Vol. 76, pp. 100-109, (2017) (PubMed).

Aliase für CD47 Proteine

alkaline phosphatase, intestinal (ALPI) Proteine
CD47 molecule (CD47) Proteine
CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47) Proteine
Cd47 molecule (Cd47) Proteine
9130415E20Rik Proteine
AA407862 Proteine
AI848868 Proteine
AW108519 Proteine
B430305P08Rik Proteine
CD47/IAP Proteine
IAP Proteine
Itgp Proteine
MER6 Proteine
OA3 Proteine
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