CD47 Proteine
(CD47)
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].
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CD47
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
1 image
CD47
Spezies: Human
Wirt: HEK-293T Cells
Recombinant
WB, SDS, ELISA, PI
1 image
CD47
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Func
Active
CD47
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
CD47
Spezies: Hund
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by reduced SDS-PAGE.
Active
CD47
Spezies: Rhesusaffen, Cynomolgus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Func
Active
CD47
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
CD47
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
CD47
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
CD47
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CD47
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CD47
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
CD47
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD47
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD47
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
CD47
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
CD47
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
CD47
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
CD47
Spezies: Maus
Wirt: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, ELISA, Imm, AcA
Active
CD47
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
Aktuelle Publikationen für unsere CD47 Proteine
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).: "CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 8, Issue 2, (2020) (PubMed).
: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).
: "Cancer immunotherapy targeting the CD47/SIRPα axis." in: European journal of cancer (Oxford, England : 1990), Vol. 76, pp. 100-109, (2017) (PubMed).
Aliase für CD47 Proteine
alkaline phosphatase, intestinal (ALPI) ProteineCD47 molecule (CD47) Proteine
CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47) Proteine
Cd47 molecule (Cd47) Proteine
9130415E20Rik Proteine
AA407862 Proteine
AI848868 Proteine
AW108519 Proteine
B430305P08Rik Proteine
CD47/IAP Proteine
IAP Proteine
Itgp Proteine
MER6 Proteine
OA3 Proteine
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