CD33 Proteine
(CD33)
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
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CD33
Spezies: Human
Wirt: Human Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
CD33
Spezies: Human
Wirt: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
ELISA, WB
CD33
Spezies: Human
Wirt: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
ELISA, WB
CD33
Spezies: Maus
Wirt: Mammalian Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
CD33
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CD33
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, ELISA, WB
CD33
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
CD33
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 80 % as determined by SDS-PAGE.
ELISA, WB
CD33
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 85 % as determined by reducing SDS-PAGE.
CD33
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % pure
SDS
CD33
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
CD33
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>95 %
SDS, ELISA, WB, IP
1 image
CD33
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
1 image
CD33
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
MALS verified
CD33
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
95 %
MALS verified
CD33
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
95,00 %
Aktuelle Publikationen für unsere CD33 Proteine
: "Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression." in: Scientific reports, Vol. 7, Issue 1, pp. 270, (2017) (PubMed).: "Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia." in: Oncoimmunology, Vol. 5, Issue 9, pp. e1211220, (2016) (PubMed).
Aliase für CD33 Proteine
CD33 molecule (CD33) ProteineCD33 antigen (Cd33) Proteine
CD33 molecule (Cd33) Proteine
gp67 Proteine
p67 Proteine
SIGLEC-3 Proteine
Siglec-3 Proteine
SIGLEC3 Proteine
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