CD1c Produkte
(T-cell surface glycoprotein CD1c (CD1C))
Kategorien
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008].
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Ausgewählte CD1c Kategorien
CD1c Antikörper
High quality antibodies with extensive validation data.
CD1c Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CD1c Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, FACS, IHC, ICC, Neut
Validierungen
- (5)
Kat. Nr.
ABIN5611307
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, IHC, IP
Validierungen
- (4)
- (3)
Kat. Nr.
ABIN1981870
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS
Validierungen
- (4)
Kat. Nr.
ABIN6240833
Menge
100 tests
Datenblatt
Datenblatt
Empfohlene CD1c Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348558
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3090982
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3097180
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CD1c Produkten
: "Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e113840, (2014) (PubMed).: "The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation." in: Immunity, Vol. 33, Issue 6, pp. 853-62, (2010) (PubMed).
: "Membrane trafficking of CD1c on activated T cells." in: Journal of leukocyte biology, Vol. 70, Issue 4, pp. 567-77, (2001) (PubMed).
: "Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens." in: The Journal of experimental medicine, Vol. 192, Issue 2, pp. 281-8, (2000) (PubMed).
: "Increased numbers of dendritic cells in the bronchiolar tissues of diffuse panbronchiolitis." in: American journal of respiratory and critical care medicine, Vol. 162, Issue 1, pp. 148-53, (2000) (PubMed).
Synonyme und alternative Namen zu CD1c
CD1c molecule (CD1C), BDCA1, CD1, CD1A, R7Bezeichner auf Proteinebene für CD1c
- CD1C antigen, c polypeptide
- T-cell surface glycoprotein CD1c
- cortical thymocyte antigen CD1C
- differentiation antigen CD1-alpha-3
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