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CD1a Proteine

(CD1a)
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

Häufig verwendete CD1a Proteine

Aktuelle Publikationen für unsere CD1a Proteine

Bechan, Lee, Zajonc, Heckel, Xian, Throsby, van Meijer, Germeraad, Kruisbeek, Egeler, Arceci: "Phage display generation of a novel human anti-CD1A monoclonal antibody with potent cytolytic activity." in: British journal of haematology, Vol. 159, Issue 3, pp. 299-310, (2012) (PubMed).

Aliase für CD1a Proteine

CD1a molecule (CD1A) Proteine
CD1 antigen (CD1.1) Proteine
T-cell surface glycoprotein CD1a (LOC100156095) Proteine
T-cell surface glycoprotein CD1a (LOC101111409) Proteine
CD1 Proteine
CD1A Proteine
FCB6 Proteine
HTA1 Proteine
R4 Proteine
T6 Proteine
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