The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012].
Pierog, Krishna, Yamniuk, Chauhan, DeSilva: "Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples." in: Journal of immunological methods, Vol. 416, pp. 124-36, (2015) (PubMed).
Aliase für CD16 Proteine
Fc fragment of IgG, low affinity IIa, receptor (Fcgr2a) Proteine Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A) Proteine Fc fragment of IgG receptor IIIb (FCGR3B) Proteine Fc fragment of IgG receptor IIIa (FCGR3A) Proteine Fc receptor, IgG, low affinity III (Fcgr3) Proteine Fc-gamma RIII (FCGR3) Proteine CD16 Proteine CD16b Proteine FCG3 Proteine Fcgr3 Proteine FCGR3 Proteine FCGR3@ Proteine Fcgr3a Proteine FCR-10 Proteine FCRIII Proteine FcRIII Proteine FCRIIIb Proteine