CCL2 Proteine
(Chemokine (C-C Motif) Ligand 2 (CCL2))
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008].
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CCL2
Spezies: Rhesusaffen
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
CCL2
Spezies: Chinese Hamster
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
CCL2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90% by SDS - PAGE
SDS, AcA
Active
CCL2
Spezies: Maus
Wirt: HEK-293T Cells
Recombinant
> 98 % as analyzed by SDS-PAGE.
Active
CCL2
Spezies: Ratte
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS
Rockland 009-001-b60
CCL2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
98,00%
SDS
1 image
Rockland Original
CCL2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
CCL2
Spezies: Kaninchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, ELISA, IP
1 image
CCL2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
CCL2
Spezies: E. coli
Wirt: Hefe
Recombinant
> 90 %
SDS
1 image
CCL2
Spezies: Meerschweinchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, ELISA, IP
1 image
CCL2
Spezies: Pferd
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, ELISA, IP
1 image
CCL2
Spezies: Affe
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, ELISA, IP
1 image
CCL2
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
< 98 % by SDS-PAGE gel and HPLC analyses.
Active
CCL2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
SDS, WB, ELISA, MS
CCL2
Spezies: Maus
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
SDS, WB, ELISA, MS
Aktuelle Publikationen für unsere CCL2 Proteine
: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).: "NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis." in: Circulation, Vol. 127, Issue 18, pp. 1888-902, (2013) (PubMed).
: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).
: "Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 26, Issue 8, pp. 1746-52, (2006) (PubMed).
: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).
: "Leukocyte migration and activation by murine chemokines." in: Immunobiology, Vol. 195, Issue 4-5, pp. 499-521, (1997) (PubMed).
: "Chemokines." in: Blood, Vol. 90, Issue 3, pp. 909-28, (1997) (PubMed).
: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).
: "Biochemical and biologic characterization of murine monocyte chemoattractant protein-1. Identification of two functional domains." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 7, pp. 3541-9, (1994) (PubMed).
: "Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 8, pp. 3708-16, (1994) (PubMed).
Aliase für CCL2 Proteine
C-C motif chemokine ligand 2 (CCL2) Proteinechemokine (C-C motif) ligand 2 (Ccl2) Proteine
C-C motif chemokine ligand 2 (Ccl2) Proteine
chemokine (C-C motif) ligand 2 (CCL2) Proteine
C-C motif chemokine 2 (LOC101120093) Proteine
AI323594 Proteine
GDCF-2 Proteine
HC11 Proteine
HSMCR30 Proteine
JE Proteine
MCAF Proteine
MCP-1 Proteine
MCP-1A Proteine
MCP1 Proteine
MCP1A Proteine
SCYA2 Proteine
Scya2 Proteine
Sigje Proteine
SMC-CF Proteine
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