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Human Polyclonal RANBP2 Primary Antibody für IP, WB - ABIN408616
Wang, Yan, Liu, Liu, Lin, Liu, Chen, Zhang, Xu, Shi, Li, Zhao, Meng, Xia, Li, Zhu: HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells. in Nature communications 2017
Cow (Bovine) Polyclonal RANBP2 Primary Antibody für IHC (p), IHC - ABIN266970
Hamard, Boyer-Guittaut, Camuzeaux, Dujardin, Hauss, Oelgeschläger, Vigneron, Kedinger, Chatton: Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity. in Nucleic acids research 2007
Human Polyclonal RANBP2 Primary Antibody für ICC, IF - ABIN3201003
Yokoyama, Hayashi, Seki, Panté, Ohba, Nishii, Kuma, Hayashida, Miyata, Aebi: A giant nucleopore protein that binds Ran/TC4. in Nature 1995
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q.
358 kDa nucleoporin
, E3 SUMO-protein ligase RanBP2
, nuclear pore complex protein Nup358
, nucleoporin 358
, nucleoporin Nup358
, ran-binding protein 2
, transformation-related protein 2
, RAN binding protein 2
, e3 SUMO-protein ligase RanBP2-like