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Calsyntenin 1 Proteine

(Calsyntenin 1 (CLSTN1))
Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2- mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1- binding. May modulate calcium-mediated postsynaptic signals (By similarity).

2 Treffer :

CLSTN1 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
Produktnummer ABIN1349745
 
CLSTN1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2713079
 
  • Typ Protein
    • Protein
  • Anwendung
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • ELISA
    • Standard (STD)
    • Western Blotting (WB)
  • Reaktivität
    • Human
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 1-971
    • Transcript Variant 1
  • Konjugat
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Hersteller
    • OriGene
    • antibodies-online

Aliase für Calsyntenin 1 Proteine

calsyntenin 1 (CLSTN1) Proteine
calsyntenin 1 (clstn1) Proteine
calsyntenin 3 (clstn3) Proteine
beta-catenin-interacting protein 1 (LOC100356725) Proteine
calsyntenin-1 (LOC100435584) Proteine
calsyntenin 1 (Clstn1) Proteine
beta-catenin-interacting protein 1 (LOC479600) Proteine
1810034E21Rik Proteine
ALC-ALPHA Proteine
alcalpha1 Proteine
alcalpha2 Proteine
CALSYNTENIN-1 Proteine
CDHR12 Proteine
clstn1 Proteine
Cst-1 Proteine
Cstn1 Proteine
CSTN1 Proteine
fm67g03 Proteine
PIK3CD Proteine
wu:fk52g02 Proteine
wu:fm67g03 Proteine
XB31alpha Proteine
zgc:56528 Proteine
zgc:153744 Proteine
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