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anti-Human COX2 Antikörper:
anti-Mouse (Murine) COX2 Antikörper:
anti-Rat (Rattus) COX2 Antikörper:
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Human Monoclonal COX2 Primary Antibody für WB - ABIN283213
Cheng, Whitehead, Hachinski, Cechetto: Effects of pyrrolidine dithiocarbamate on beta-amyloid (25-35)-induced inflammatory responses and memory deficits in the rat. in Neurobiology of disease 2006
COX-2 has been found to be overexpressed in Sinonasal Inverted Papilloma , and most likely plays an important role in the process of malignant transformation from Sinonasal Inverted Papilloma to Squamous Cell Carcinoma.
Expression of COX-2 in adenocarcinomas of the esophagogastric junction seems to have no prognostic effect or impact on patients' survival but is associated with favourable clinicopathologic factors
Topical application of glycolic acid suppresses the UVB induced IL-6 (zeige IL6 Antikörper), IL-8 (zeige IL8 Antikörper), MCP-1 (zeige CCL2 Antikörper) and COX-2 inflammation by modulating NF-kappaB (zeige NFKB1 Antikörper) signaling pathway in keratinocytes.
the present study identified a positive correlation between EpCAM (zeige EPCAM Antikörper) and COX-2 expression in breast cancer cell lines and tissue specimens. EpCAM (zeige EPCAM Antikörper) and COX-2 were associated with the prognosis of breast cancer patients.
Intra-tumour activation of the PTEN/Akt (zeige AKT1 Antikörper)/COX-2 pathway modulates colorectal cancer (CRC (zeige CALR Antikörper)) progression and invasive capacity.
Data suggest that mutations in MT-CO2 and MT-ND5 (zeige MT-ND5 Antikörper) can be involved in MIDD (maternally inherited diabetes and deafness); a Tunisian family (mother, daughter, son) with clinical features of MIDD associated with retinopathy exhibit mutations in MT-CO2 (m.8241T>G - p. F219C) and MT-ND5 (zeige MT-ND5 Antikörper) (m.13276G>A - p. M314V); these two mutations could explain retinopathy in some family members. (MT-ND5 (zeige MT-ND5 Antikörper) = NADH dehydrogenase subunit 5 (zeige MT-ND5 Antikörper))
Results demonstrates that the presence of high levels of COX-2 is associated with poor prognosis for breast cancer patients and predicts bigger tumor size and lymph node metastasis. [metastasis]
Tumor-infiltrating M2 macrophages could induce vasculogenic mimicry by up-regulating COX-2 expression in glioblastoma multiforme cells.
The results of this study show suppression of COX-2 in gingival tissue after low-level laser treatment as adjunct to scaling and root planing.
cyclooxygenase-2 (zeige PTGS2 Antikörper) is differentially expressed in metastatic melanoma, which has a role in progression free survival
These findings suggest that nuclear factor kappa B(NF-kappaB (zeige NFKB1 Antikörper)) and cyclooxygenase-2 (zeige PTGS2 Antikörper) play roles in epidermal cell regeneration following beta-irradiation of mini-pig skin.
B1 receptors are coupled to COX2 (zeige PTGS2 Antikörper) in causing endothelium-independent contractions in endotoxin-treated pig coronary arteries
COX2 (zeige PTGS2 Antikörper) expression is upregulated in CAVD, and its activity contributes to osteogenic gene induction and valve calcification in vitro and in vivo.
These results suggest that COX-2 (zeige PTGS2 Antikörper) plays a role in the pathogenesis of Mycoplasma hyopneumoniae -infection.
Brain death increases the expression of COX-1 (zeige COX1 Antikörper) and COX-2 (zeige PTGS2 Antikörper) mRNA in the renal medulla
Expression of COX-2 (zeige PTGS2 Antikörper) was strongest in gilts with acute endometritis, but did not differ between those with chronic endometritis and normal endometrium.
COX-2 (zeige PTGS2 Antikörper) is differentially expressed in normal versus lungworm-infected lungs of pigs and is likely to be involved in the pathogenesis of porcine parasitic bronchopneumonia.
In porcine vas (zeige AVP Antikörper) deferens epithelial cell monolayers, increases in anion secretion were associated with preferential upregulation of PTGS2 (zeige PTGS2 Antikörper) at the mRNA and protein levels.
expression appears to be positively and negatively regulated by p38 MAPK (zeige MAPK14 Antikörper) and JNK (zeige MAPK8 Antikörper) pathways; alternatively, ERK1/2 appear to be involved in COX-2 (zeige PTGS2 Antikörper)-independent reparative events that remain to be defined
Neutrophils augment recovery of transepithelial electrical resistance in ischemia-injured ileal mucosa via IL-1beta (zeige IL1B Antikörper)-dependent upregulation of COX-2 (zeige PTGS2 Antikörper). (Cyclooxygenase 2 (zeige PTGS2 Antikörper))
Topical application of glycolic acid suppresses the UVB induced IL-6 (zeige IL6 Antikörper), IL-8 (zeige IL8 Antikörper), MCP-1 (zeige CPT1B Antikörper) and COX-2 inflammation by modulating NF-kappaB (zeige NFKB1 Antikörper) signaling pathway in mouse skin.
COX-2/mPGES-1 (zeige PTGES Antikörper)/PGE2 cascade activation mediates uric acid-induced glomerular mesangial cell proliferation.
Cobalt protoporphyrin induces COX-2 expression through activating P2X7 (zeige P2RX7 Antikörper) receptors and ASK1 (zeige MAP3K5 Antikörper)/MAP kinases as well as PIAS1 (zeige PIAS1 Antikörper) degradation signaling pathways.
sUV activated the transcription factors nuclear factor-kappaB and activator protein-1 (zeige JUN Antikörper) which, in turn, induces COX-2 expression.
Results indicate that Cox-2 promotes Col10a1 (zeige COL10A1 Antikörper) expression and chondrocyte hypertrophy in vitro.
These data reveal important structure-function and signaling differences between the two FFA4 isoforms, and for the first time link FFA4 to modulation of ROS (zeige ROS1 Antikörper) in macrophages.
Our data suggest that there are physiologically important gender differences in hypoxic acclimatization in COX-2-deficient mice. The COX-2 signaling pathway appears to be required for acclimatization in oxygen-limiting environments only in males, whereas female COX-2-deficient mice may be able to access COX-2-independent mechanisms to achieve hypoxic acclimatization.
increased COX2 expression has an impact on the aging process
These results establish a novel signaling process whereby PAK1 (zeige PAK1 Antikörper) upregulates COX-2, reduces anandamide levels and restricts tonic endocannabinoids-mediated processes.
Angiotensin II-AT1-receptor (zeige AGTRAP Antikörper) signaling is necessary for COX-2-dependent normal postnatal nephrogenesis and maturation.
The objective of this study was to evaluate the mRNA expression of prostaglandin-endoperoxide synthase 2 (PTGS 2 (zeige PTGS2 Antikörper)), prostaglandin F2alpha synthase (PTGFS) and prostaglandin E2 microsomal synthase 1 (mPTGES 1) in the endometrium of repeat-breeding cows with and without subclinical endometritis.
results indicate that nuclear receptor subfamily 1 group D member 1(REV-ERBalpha (zeige NR1D1 Antikörper)) plays an inhibitory role in the expression of prostaglandin-endoperoxide synthase 2(PTGS2 (zeige PTGS2 Antikörper)) in both bovine USCs and UECs treated with ovarian steroids
This study showed that neutrophils from periparturient heifers show impairment of COX-2 (zeige PTGS2 Antikörper) mRNA expression and lactoferrin (zeige LTF Antikörper), suggesting that these mechanisms may contribute to immunosuppression in cows around calving.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (zeige IL8 Antikörper) and PTGS2 (zeige PTGS2 Antikörper), and decreased the expression of SOD2 (zeige SOD2 Antikörper), GPX3 (zeige GPX3 Antikörper), DAB2 (zeige DAB2 Antikörper), and NR3C1 (zeige NR3C1 Antikörper). TNF (zeige TNF Antikörper) and IL6 (zeige IL6 Antikörper) levels were also decreased while those of NAMPT (zeige NAMPT Antikörper) were unaffected.
Purinergic P2Y1 receptor (zeige P2RY1 Antikörper) signaling mediates wound stimuli-induced cyclooxygenase-2 (zeige PTGS2 Antikörper) expression in intestinal subepithelial myofibroblasts
Data suggest that Escherichia coli infections (here, administration of LPS (zeige IRF6 Antikörper)) provokes luteolysis in diestrus, non-lactating cows but no change in expression of PTGS2 (zeige PTGS2 Antikörper) in corpus luteum and has no effect on luteinization in the following cycle.
Data indicate that the proton-pumping pathway of heart cytochrome c (zeige CYCS Antikörper) oxidase includes a hydrogen-bond network and a water channel (zeige AQP4 Antikörper) located in tandem between the positive and negative side of the mitochondrial membrane.
Study suggests that His503 is involved in the proton supply to the D-path as a proton acceptor in cytochrome c (zeige CYCS Antikörper) oxidase.
Data suggest that the axial Met residue moderately increased the redox potential of the Cu(A) site in cytochrome c (zeige CYCS Antikörper) oxidase.
Studies indicate that heart cytochrome c (zeige CYCS Antikörper) oxidase subunits I, II and III are encoded by the mitochondrial genome.
Pretreatment of cells with selective COX-2 blocker etodolac markedly inhibited ICl.
Safflower injection may attenuate lung ischemia/reperfusion injury through inhibiting cyclooxygenase-2 (zeige PTGS2 Antikörper) expression.
The RNA interference targeting COX-2 can effectively inhibit the expression of COX-2 and MMP-2 (zeige MMP2 Antikörper) in IL-1alpha stimulated rabbit corneal stromal cells in vitro.
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
PGH synthase 2
, PHS II
, cyclooxygenase 2b
, prostaglandin G/H synthase 2
, prostaglandin H2 synthase 2
, cyclooxygenase 2
, glucocorticoid-regulated inflammatory cyclooxygenase
, macrophage activation-associated marker protein P71/73
, cytochrome c oxidase subunit II
, cytochrome c oxidase subunit ii
, cytochrome C oxidase subunit II
, cyclooxygenase type 2
, prostaglandin G/H synthase-2