Der Kaninchen Polyklonal anti-COX2 Antikörper wird verwendet zum Nachweis von COX2 in Proben von Human und Maus. Er wurde validiert für WB und IHC (p).
COX2
Reaktivität: Human
WB, IHC
Wirt: Kaninchen
Monoclonal
unconjugated
Applikationshinweise
Titration of the COX-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
The lyophilized COX-2 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
COX2
(Cytochrome C Oxidase Subunit II (COX2))
Andere Bezeichnung
COX2
Hintergrund
Cyclooxygenase (COX) is the key enzyme in conversion of arachidonic acid to PGs. The COX2 gene encodes an inducible prostaglandin synthase enzyme that is overexpressed in adenocarcinomas and other tumors. Deletion of the murine gene in Min mice reduced the incidence of intestinal tumors, suggesting that it is required for tumorigenesis.