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BLK Produkte

(B Lymphoid Tyrosine Kinase (BLK))

Kategorien

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010].

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Ausgewählte BLK Kategorien

BLK Antikörper

High quality antibodies with extensive validation data.

BLK ELISA Kits

Reliable ELISA kits for a wide range of species.

BLK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BLK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), IHC (fro), ICC
Validierungen
  • (6)
Kat. Nr. ABIN7441157
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN560064
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN392087
Menge 400 μL
Datenblatt Datenblatt

Empfohlene BLK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954026
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4885999
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951074
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BLK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (2)
Kat. Nr. ABIN5570560
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346709
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346711
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BLK Produkten

Bernal-Quirós, Wu, Alarcón-Riquelme, Castillejo-López: "BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling." in: PLoS ONE, Vol. 8, Issue 3, pp. e59842, (2013) (PubMed).

Chen, Felix, Wang: "Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 5684-92, (2011) (PubMed).

Castillejo-López, Delgado-Vega, Wojcik, Kozyrev, Thavathiru, Wu, Sánchez, Pöllmann, López-Egido, Fineschi, Domínguez, Lu, James, Merrill, Kelly, Kaufman, Moser, Gilkeson, Frostegård, Pons-Estel et al.: "Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. ..." in: Annals of the rheumatic diseases, Vol. 71, Issue 1, pp. 136-42, (2011) (PubMed).

Yang, Ng, Zhao, Hirankarn, Lau, Mok, Chan, Wong, Lee, Mok, Wong, Avihingsanon, Lee, Ho, Lee, Wong, Lau: "Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese." in: Genes and immunity, Vol. 10, Issue 3, pp. 219-26, (2009) (PubMed).

Borowiec, Liew, Thompson, Boonyasrisawat, Hu, Mlynarski, El Khattabi, Kim, Marselli, Rich, Krolewski, Bonner-Weir, Sharma, Sale, Mychaleckyj, Kulkarni, Doria: "Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 34, pp. 14460-5, (2009) (PubMed).

Hom, Graham, Modrek, Taylor, Ortmann, Garnier, Lee, Chung, Ferreira, Pant, Ballinger, Kosoy, Demirci, Kamboh, Kao, Tian, Gunnarsson, Bengtsson, Rantapää-Dahlqvist, Petri, Manzi, Seldin, Rönnblom et al.: "Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. ..." in: The New England journal of medicine, Vol. 358, Issue 9, pp. 900-9, (2008) (PubMed).

Chen, Huang, Wang: "Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity." in: Blood, Vol. 109, Issue 10, pp. 4360-7, (2007) (PubMed).

Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

Synonyme und alternative Namen zu BLK

BLK proto-oncogene, Src family tyrosine kinase (blk), BLK proto-oncogene, Src family tyrosine kinase (BLK), B lymphoid kinase (Blk), BLK proto-oncogene, Src family tyrosine kinase (Blk), bltk, MODY11, si:dkey-33i22.2, zgc:136231

Bezeichner auf Proteinebene für BLK

  • B lymphoid kinase
  • tyrosine-protein kinase Blk
  • B lymphoid tyrosine kinase
  • tyrosine-protein kinase Blk-like
  • b lymphocyte kinase
  • p55-Blk
  • BLK nonreceptor tyrosine kinase
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