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Bestrophin 3 Produkte

(Bestrophin 3 (BEST3))

Kategorien

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD\; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]\; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008].

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Ausgewählte Bestrophin 3 Kategorien

Bestrophin 3 Antikörper

High quality antibodies with extensive validation data.

Bestrophin 3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Bestrophin 3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Bat, Cow, Dog, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation IHC, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN461699
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN1539351
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN6745454
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Bestrophin 3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6202077
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Bestrophin 3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346635
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3089767
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3123494
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Bestrophin 3 Produkten

Golubinskaya, Elvin, Ebefors, Gustafsson, Mallard, Nyström, Nilsson: "Bestrophin-3 is differently expressed in normal and injured mouse glomerular podocytes." in: Acta physiologica (Oxford, England), Vol. 214, Issue 4, pp. 481-96, (2015) (PubMed).

Jiang, Liu, Ma, Tang, Zhou, Guan: "Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 5, pp. 556-65, (2013) (PubMed).

Wang, Yang, Zheng, Zhang, Tang, Wang, Du, Lv, Liu, Zhou, Guan: "Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation." in: Circulation, Vol. 125, Issue 5, pp. 697-707, (2012) (PubMed).

Lee, Chakraborty, Roussa, Wolff, Thévenod: "ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP." in: Biochimica et biophysica acta, Vol. 1823, Issue 10, pp. 1864-76, (2012) (PubMed).

Broegger, Jacobsen, Secher Dam, Boedtkjer, Kold-Petersen, Pedersen, Aalkjaer, Matchkov: "Bestrophin is important for the rhythmic but not the tonic contraction in rat mesenteric small arteries." in: Cardiovascular research, Vol. 91, Issue 4, pp. 685-93, (2011) (PubMed).

Matchkov, Larsen, Bouzinova, Rojek, Boedtkjer, Golubinskaya, Pedersen, Aalkjaer, Nilsson: "Bestrophin-3 (vitelliform macular dystrophy 2-like 3 protein) is essential for the cGMP-dependent calcium-activated chloride conductance in vascular smooth muscle cells." in: Circulation research, Vol. 103, Issue 8, pp. 864-72, (2008) (PubMed).

Synonyme und alternative Namen zu Bestrophin 3

bestrophin 3 (BEST3), Bestrophin 3 (Best3), bestrophin 3 (best3), bestrophin 3 (Best3), best-3, BEST3, bestrophin-3, CG12327, dbest3, Dmel\\CG12327, mBest4, VMD2L3, Vmd2l3

Bezeichner auf Proteinebene für Bestrophin 3

  • bestrophin 3
  • CG12327-PA
  • Best3-PA
  • bestrophin-3
  • bestrophin-3-like
  • vitelliform macular dystrophy 2-like 3
  • vitelliform macular dystrophy 2-like protein 3
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