BAFF Proteine
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
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56 Treffer
TNFSF13B
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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TNFSF13B
Spezies: Human
Wirt: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
TNFSF13B
Spezies: Human, Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % (SDS-PAGE)
SDS
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
TNFSF13B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
TNFSF13B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
TNFSF13B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
TNFSF13B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS-PAGE.
Active
TNFSF13B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
TNFSF13B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 88 % as determined by reducing SDS-PAGE.
TNFSF13B
Spezies: Human, Maus
Wirt: CHO Cells
Recombinant
>95 % (SDS-PAGE)
SDS
Active
TNFSF13B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 92 % by SDS-PAGE.
Active
TNFSF13B
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13B
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
Aktuelle Publikationen für unsere BAFF Proteine
: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).: "Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses." in: European journal of immunology, Vol. 41, Issue 3, pp. 787-97, (2011) (PubMed).
: "TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts." in: Blood, Vol. 111, Issue 3, pp. 1004-12, (2008) (PubMed).
: "Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway." in: Blood, Vol. 103, Issue 2, pp. 679-88, (2004) (PubMed).
Aliase für BAFF Proteine
TNF superfamily member 13b (TNFSF13B) ProteineTNF receptor superfamily member 13C (TNFRSF13C) Proteine
TNF superfamily member 13b (Tnfsf13b) Proteine
tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B) Proteine
TNF receptor superfamily member 13C (Tnfrsf13c) Proteine
tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b) Proteine
tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c) Proteine
tumor necrosis factor superfamily member 13b (TNFSF13B) Proteine
TNF superfamily member 13b (tnfsf13b) Proteine
2010006P15Rik Proteine
BAFF Proteine
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prolixin Proteine
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