BAFF Proteine
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
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TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 94 % as determined by HPLC
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95% as determined by Tris-Bis PAGE,> 94% as determined by HPLC
TNFSF13B
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
custom-made
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
TNFSF13B
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TNFSF13B
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
TNFSF13B
Spezies: Human
Wirt: HEK-293T Cells
Recombinant
SDS, WB, ELISA, PI
2 Abbildungen
TNFSF13B
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
TNFSF13B
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
TNFSF13B
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Func
Active
TNFSF13B
Spezies: Maus
Wirt: Human Cells
Recombinant
>95 % as determined by reducing SDS-PAGE.
1 image
TNFSF13B
Spezies: Human, Maus
Wirt: HEK-293 Cells
Recombinant
>90 % (SDS-PAGE)
SDS
1 reference
TNFSF13B
Spezies: Human, Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % (SDS-PAGE)
SDS
Active
2 Referenzen
TNFSF13B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
WB, ELISA
1 image
TNFSF13B
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
Aktuelle Publikationen für unsere BAFF Proteine
: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).: "Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses." in: European journal of immunology, Vol. 41, Issue 3, pp. 787-97, (2011) (PubMed).
: "TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts." in: Blood, Vol. 111, Issue 3, pp. 1004-12, (2008) (PubMed).
: "Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway." in: Blood, Vol. 103, Issue 2, pp. 679-88, (2004) (PubMed).
Aliase für BAFF Proteine
TNF superfamily member 13b (TNFSF13B) ProteineTNF receptor superfamily member 13C (TNFRSF13C) Proteine
TNF superfamily member 13b (Tnfsf13b) Proteine
tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B) Proteine
TNF receptor superfamily member 13C (Tnfrsf13c) Proteine
tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b) Proteine
tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c) Proteine
tumor necrosis factor superfamily member 13b (TNFSF13B) Proteine
TNF superfamily member 13b (tnfsf13b) Proteine
2010006P15Rik Proteine
BAFF Proteine
BAFF-R Proteine
BAFFR Proteine
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Bcmd Proteine
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Bcmd1 Proteine
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CD257 Proteine
CD268 Proteine
CVID4 Proteine
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DTL Proteine
Lvis22 Proteine
prolixin Proteine
RGD1560810 Proteine
RGD1561519 Proteine
TALL-1 Proteine
TALL1 Proteine
THANK Proteine
TNFSF13B Proteine
TNFSF20 Proteine
zgc:172115 Proteine
ZTNF4 Proteine
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