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AVPR2 Proteine

(Arginine Vasopressin Receptor 2 (AVPR2))
This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing. [provided by RefSeq, Jul 2008].

6 Treffer

custom-made AVPR2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7545055
 
AVPR2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Produktnummer ABIN7413085
 
AVPR2 Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc Imm, ELISA, cryo-EM, PhD, SPR
Produktnummer ABIN7596967
 
AVPR2 Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538139
 
custom-made AVPR2 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Produktnummer ABIN3097306
 
AVPR2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant SDS, WB
Produktnummer ABIN6377843
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Phage Display (PhD)
    • Positive Control (PC)
    • Surface Plasmon Resonance (SPR)
    • Cryogenic electron microscopy (cryo-EM)
  • Reaktivität
    • Human
    • Mouse
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Mammalian Cells
  • Bindungsspezifität
    • AA 1-371
  • Konjugat
    • His tag
    • Unkonjugiert
    • DYKDDDDK Tag,Strep Tag
    • Strep Tag
  • Protein-Typ
    • Recombinant
    • Synthetic Nanodisc
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online
    • Abbexa

Aliase für AVPR2 Proteine

arginine vasopressin receptor 2 (AVPR2) Proteine
arginine vasopressin receptor 2 (Avpr2) Proteine
ADHR Proteine
AVPR2 Proteine
DI1 Proteine
DIR Proteine
DIR3 Proteine
ND1 Proteine
NDI Proteine
V2R Proteine
VPV2R Proteine
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