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Aubergine Antikörper (Internal Region)

aub Reaktivität: Drosophila melanogaster ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129699
  • Target
    Aubergine (aub)
    Bindungsspezifität
    Internal Region
    Reaktivität
    Drosophila melanogaster
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Applikation
    ELISA, Western Blotting (WB)
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of Drosophila melanogaster Aubergine/Sting protein.
    Isotyp
    IgG
  • Applikationshinweise
    Aubergine affinity-purified antibody has been tested for use in ELISA. Specific conditions for reactivity should be optimized by the end user. By western blot a band approximately 98 kDa in size corresponding to Aubergine protein is expected in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Lagerung
    -20 °C
  • Target
    Aubergine (aub)
    Andere Bezeichnung
    Aubergine/Sting
    Synonyme
    AUB antikoerper, Aub antikoerper, CG6137 antikoerper, Dmel\\CG6137 antikoerper, ms(2)32D antikoerper, sti antikoerper, sting antikoerper, GB10293 antikoerper, Piwi antikoerper, SIWI antikoerper, siwi1 antikoerper, aubergine antikoerper, aubergine protein antikoerper, aub antikoerper, Aubergine antikoerper
    Substanzklasse
    Species
    Hintergrund
    Aubergine (Sting) is a Drosophila protein involved in germ-line development and RNA interference.  Drosophila melanogaster has a robust and efficient innate immune system, which reacts to infections ranging from bacteria to fungi and, as discovered recently, viruses as well. The known Drosophila immune responses rely on humoral and cellular activities, similar to those found in the innate immune system of other animals. Recently, RNAi or 'RNA silencing' has arisen as a possible means by which Drosophila can react to specific pathogens, transposons and retroviral elements, in a fashion similar to that of a traditional mammalian adaptive immune system instead of in a more generalized and genome encoded innate immune-based response. RNAi is a highly conserved regulation and defense mechanism, which suppresses gene expression via targeted RNA degradation directed by either exogenous dsRNA (cleaved into siRNAs) or endogenous miRNAs. In plants, RNAi has been found to act as an antiviral immune response system. In Drosophila multiple core RNAi pathway genes have been reported, including piwi, vasa intronic gene (vig), aubergine (aub), armitage (armi), Rm62, r2d2 and Argonaute2 (AGO2).
    Synonyms: AUBERGINE Aubergine, isoform A Sting
    Gen-ID
    34524, 17136494
    UniProt
    O76922
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