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N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Produkte

(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))

Kategorien

This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Kategorien

N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Antikörper

High quality antibodies with extensive validation data.

N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7434806
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN513533
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN7142987
Menge 100 μL
Datenblatt Datenblatt

Empfohlene N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958012
Menge 96 tests
Datenblatt Datenblatt

Empfohlene N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1345778
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124089
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345780
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Produkten

Cho, Lee, Liu, Wang, Kwon: "A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase." in: ACS chemical biology, Vol. 14, Issue 1, pp. 11-19, (2019) (PubMed).

Yildiz-Ozer, Oztopcu-Vatan, Kus: "The investigation of ceranib-2 on apoptosis and drug interaction with carboplatin in human non small cell lung cancer cells in vitro." in: Cytotechnology, Vol. 70, Issue 1, pp. 387-396, (2018) (PubMed).

Realini, Palese, Pizzirani, Pontis, Basit, Bach, Ganesan, Piomelli: "Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION." in: The Journal of biological chemistry, Vol. 291, Issue 5, pp. 2422-34, (2016) (PubMed).

Tan, Liu, Fox, Barth, Sharma, Turner, Awwad, Dewey, Doi, Spitzer, Shah, Morad, Desai, Amin, Zhu, Liao, Yun, Kester, Claxton, Wang, Cabot, Schuchman, Levine, Feith, Loughran: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).

Elamin, Titz, Dijon, Merg, Geertz, Schneider, Martin, Schlage, Frentzel, Talamo, Phillips, Veljkovic, Ivanov, Vanscheeuwijck, Peitsch, Hoeng: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).

Cai, Lucki, Sewer: "Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells." in: Biochimica et biophysica acta, Vol. 1841, Issue 4, pp. 552-62, (2014) (PubMed).

Singh, Dharmarajan, Aye, Keelan: "Ceramide biosynthesis and metabolism in trophoblast syncytialization." in: Molecular and cellular endocrinology, Vol. 362, Issue 1-2, pp. 48-59, (2012) (PubMed).

Lucki, Bandyopadhyay, Wang, Merrill, Sewer: "Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 228-43, (2012) (PubMed).

Lucki, Li, Bandyopadhyay, Wang, Merrill, Sewer: "Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor." in: Molecular and cellular biology, Vol. 32, Issue 21, pp. 4419-31, (2012) (PubMed).

Sabel, Liu, Griffith, He, Xie, Lubman: "Clinical utility of serum autoantibodies detected by protein microarray in melanoma." in: International journal of proteomics, Vol. 2011, pp. 413742, (2011) (PubMed).

Synonyme und alternative Namen zu N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1

N-acylsphingosine amidohydrolase 1 (ASAH1), N-acylsphingosine amidohydrolase 1 (Asah1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog (asah1.L), N-acylsphingosine amidohydrolase (acid ceramidase) 1a (asah1a), Acid ceramidase (asah-1), N-acylsphingosine amidohydrolase (acid ceramidase) 1b (asah1b), 2310081N20Rik, AC, ACDase, ASAH, Asah, asah1, ASAH1, MGC82286, PHP, PHP32, SMAPME, zgc:66026, zgc:101637

Bezeichner auf Proteinebene für N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1

  • acid CDase
  • acid ceramidase
  • acylsphingosine deacylase
  • putative 32 kDa heart protein
  • ACDase
  • Acylsphingosine deacylase
  • N-acylsphingosine amidohydrolase 1
  • AC
  • N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • N-acylsphingosine amidohydrolase
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