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Oligodendrocytes are the myelinating cells of the central nervous system (CNS). They are the end product of a cell lineage which has to undergo a complex and precisely timed program of proliferation, migration, differentiation, and myelination to finally produce the insulating sheath of axons.(1) Myelin sheaths generated by oligodendrocytes are able to facilitate fast neuronal action potential conduction along the axon.
antibodies-online offers an excellent selection of antibodies, kits and tools for the investigation of oligodendrocytes. Below you will find hand-picked, reliable products for some of the important targets.
The following targets are directly related to research on Oligodendrocytes. Click on the links to see all available products.
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(1) Bradl M, Lassmann H. Oligodendrocytes: biology and pathology. Acta Neuropathol. 2010 Jan;119(1):37-53. doi: 10.1007/s00401-009-0601-5. Epub 2009 Oct 22. PMID: 19847447; PMCID: PMC2799635.
Barbarese, E. et al. Expression and localization of myelin basic protein in oligodendrocytes and transfected fibroblasts. J. Neurochem. 51, 1737–45 (1988).
Pozniak, C. D. et al. Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expression. Proc. Natl. Acad. Sci. U. S. A. 107, 21795–800 (2010).
Scolding, N. J. et al. Myelin-oligodendrocyte glycoprotein (MOG) is a surface marker of oligodendrocyte maturation. J. Neuroimmunol. 22, 169–176 (1989).