PDX1 Antikörper
(1 reference)-
- Target Alle PDX1 Antikörper anzeigen
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PDX1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- PDX1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PDX1 expressed in E. Coli.
- Klon
- 5A5
- Isotyp
- IgG1
- Top Product
- Discover our top product PDX1 Primärantikörper
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anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-284) antibody
PDX1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 2G12 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-30) antibodyPDX1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-30) antibodyPDX1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB15204 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-283) antibodyPDX1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 Reaktivität: Human WB, FACS, EIA Wirt: Maus Monoclonal 5A5 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 188-284) antibodyPDX1 Reaktivität: Ratte, Ziege WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 43-72) antibodyPDX1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB16670 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 429-459), (C-Term) antibodyPDX1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB02861-02862 unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36482-90, (2009) (PubMed).
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: "MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36482-90, (2009) (PubMed).
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- Target
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Andere Bezeichnung
- PDX1 (PDX1 Produkte)
- Hintergrund
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Description: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Aliases: GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1
- Molekulargewicht
- 30.8kDa
- Gen-ID
- 3651
- HGNC
- 3651
- UniProt
- P52945
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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