NOS2 Antikörper

Produktnummer ABIN969551

Der Maus Monoklonal Anti-NOS2-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, NOS2 in Proben von Human und Maus zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für NOS2 Antikörper (ABIN969551)

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NOS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon: 4E5

Produktdetails anti-NOS2 Antikörper

Verwendungszweck: NOS2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human NOS2 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-NOS2 Antikörper (ABIN969551)

Huang, Ratovitski: "Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation." in: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41422-31, (2010) (PubMed).

Granath, Norrby-Teglund, Uddman, Cardell: "Reduced iNOS expression in adenoids from children with otitis media with effusion." in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Vol. 21, Issue 8, pp. 1151-6, (2010) (PubMed).

Details zu NOS2

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Andere Bezeichnung: NOS2

Hintergrund: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.

Molekulargewicht: 131 kDa

Gen-ID: 4843

UniProt: P35228

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process