MATK Antikörper

Produktnummer ABIN969495

Dieses Anti-MATK-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MATK in WB, ELISA und FACS. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für MATK Antikörper (ABIN969495)

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MATK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 9D7

Produktdetails anti-MATK Antikörper

Verwendungszweck: MATK Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MATK expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MATK Antikörper (ABIN969495)

McShan, Zagozdzon, Park, Zrihan-Licht, Fu, Avraham, Avraham: "Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." in: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).

Details zu MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Andere Bezeichnung: MATK

Hintergrund: MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Molekulargewicht: 56 kDa

Gen-ID: 4145

UniProt: P42679